2. Gene
  3. PPP1R35 - protein phosphatase 1 regulatory subunit 35 Gene

PPP1R35 - protein phosphatase 1 regulatory subunit 35 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：蛋白磷酸酶 1 调节亚基 35

种属: Homo sapiens

同用名: C7orf47

基因 ID: 221908 | 基因类型: protein coding

关于 PPP1R35

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,435,282-100,436,698 (from NCBI)

This gene has 5 transcripts (splice variants) and 98 orthologues. Broad expression in testis (RPKM 18.3), spleen (RPKM 14.1) and 25 other tissues.

功能概要

预计可启用磷酸酶结合活性和蛋白磷酸酶抑制剂活性。预计参与磷酸酶活性的负调节。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable Phosphatase binding activity and protein Phosphatase Inhibitor activity. Predicted to be involved in negative regulation of Phosphatase activity. [provided by Alliance of Genome Resources, Apr 2022]

PPP1R35 基因产物(2)

mRNA Protein Name
NM_001346938.2 NP_001333867.1 protein phosphatase 1 regulatory subunit 35 isoform 2
NM_145030.4 NP_659467.1 protein phosphatase 1 regulatory subunit 35 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
30168418 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of centriole elongation IMP
IMP: 通过突变表型推断
30168418 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centriole IDA
IDA: 通过直接分析推断
30168418 GOA
located in centrosome IDA
IDA: 通过直接分析推断
30168418 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PPP1R35 蛋白结构

PPP1R35_C

PPP1R35_C: Protein phosphatase 1 regulatory subunit 35 C-terminus (104 - 249)

  • 0
  • 100
  • 200
  • 253 a.a.
蛋白主名 其他名称

protein phosphatase 1 regulatory subunit 35

UPF0683 protein C7orf47

关联疾病

疾病名称 别名
Bardet-Biedl Syndrome 1

BBS1

Bardet-Biedl Syndrome 1, Modifier Of

Bardet-Biedl Syndrome

BBS

Bardet-Biedl Syndrome, Type 1

Laurence-Moon-Bardet-Biedl Syndrome
Primary Autosomal Recessive Microcephaly

Autosomal Recessive Primary Microcephaly

Mcph

True Microcephaly

Microcephalia Vera

Microcephaly Vera

Microcephaly Primary Hereditary

Microcephaly, Primary, Autosomal Recessive

Primary Microcephaly
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10997 PPP1R35 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PPP1R35 VGNC VGNC:76331
Canis familiaris PPP1R35 VGNC VGNC:44893
Mus musculus PPP1R35 MGD MGI:1922853
Felis catus PPP1R35 VGNC VGNC:107810
Rattus norvegicus PPP1R35 RGD RGD:1584367
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