2. Gene
  3. FAM83B - family with sequence similarity 83 member B Gene

FAM83B - family with sequence similarity 83 member B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：具有序列相似性的家族 83 成员 B

种属: Homo sapiens

同用名: C6orf143

基因 ID: 222584 | 基因类型: protein coding

关于 FAM83B

This gene has 1 transcript (splice variant), 254 orthologues and 7 paralogues. Biased expression in skin (RPKM 10.9), esophagus (RPKM 6.8) and 12 other tissues.

功能概要

启用表皮生长因子受体结合活性；磷脂酰肌醇 3-激酶结合活性；和蛋白激酶结合活性。参与细胞群增殖和表皮生长因子受体信号通路。位于细胞质和细胞膜中。 [由基因组资源联盟提供，2022 年 4 月]

Enables epidermal growth factor receptor binding activity; phosphatidylinositol 3-kinase binding activity; and protein kinase binding activity. Involved in cell population proliferation and epidermal growth factor receptor signaling pathway. Located in cytoplasm and membrane. [provided by Alliance of Genome Resources, Apr 2022]

FAM83B 基因产物(1)

mRNA Protein Name
NM_001010872.3 NP_001010872.1 protein FAM83B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables epidermal growth factor receptor binding IPI
IPI: 通过物理相互作用推断
23912460 GOA
enables phosphatidylinositol 3-kinase catalytic subunit binding IPI
IPI: 通过物理相互作用推断
23676467 GOA
enables phosphatidylinositol 3-kinase regulatory subunit binding IPI
IPI: 通过物理相互作用推断
23676467 GOA
NOT enables phospholipase D activity IDA
IDA: 通过直接分析推断
22886302 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
23455922 GOA
enables protein kinase binding IDA
IDA: 通过直接分析推断
23676467 GOA
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
22886302 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell population proliferation IMP
IMP: 通过突变表型推断
23912460 GOA
involved in positive regulation of epidermal growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
23676467 GOA
involved in positive regulation of epidermal growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
22886302 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
22886302 GOA
located in membrane IDA
IDA: 通过直接分析推断
22886302 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FAM83B 蛋白结构

DUF1669

DUF1669: Protein of unknown function (DUF1669) (15 - 281)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1011 a.a.
蛋白主名 其他名称

protein FAM83B

FAM83B 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra FAM83B Q5T0W9 CSNK1A1 Homo sapiens P48729
Anti Tag CoIP
29789297
Intra FAM83B Q5T0W9 CSNK1A1 Homo sapiens P48729
IF
29789297
Intra FAM83B Q5T0W9 CSNK1A1 Homo sapiens P48729
Protein Kinase Assay
29789297
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Amelogenesis Imperfecta, Type Iiia

Ai3

Adhcai

Amelogenesis Imperfecta Type 3

AI3A

Amelogenesis Imperfecta, Type Iii

Amelogenesis Imperfecta, Hypocalcification Type, Autosomal Dominant

Amelogenesis Imperfecta Type 3a

Amelogenesis Imperfecta Hypomineralization Type

Amelogenesis Imperfecta Type Iii

Hypocalcified Amelogenesis Imperfecta

Amelogenesis Imperfecta, Type 3

Amelogenesis Imperfecta, Hypomineralization Type

Autosomal Dominant Amelogenesis Imperfecta Hypocalcification Type

Amelogenesis Imperfecta 3a

Amelogenesis Imperfecta Hypocalcification Type Autosomal Dominant
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04722 FAM83B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus FAM83B MGD MGI:2685362
Macaca mulatta FAM83B VGNC VGNC:72313
Felis catus FAM83B VGNC VGNC:62128
Canis familiaris FAM83B VGNC VGNC:40700
Bos taurus FAM83B VGNC VGNC:28833
Rattus norvegicus FAM83B RGD RGD:1311988
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