1. Gene
  2. Ywhae - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide Gene

Ywhae - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide Gene

种属: Mus musculus

基因 ID: 22627 | 基因类型: protein coding

关于 Ywhae

功能概要

Enables protein domain specific binding activity and protein Phosphatase binding activity. Acts upstream of or within several processes, including negative regulation of protein dephosphorylation; neuron migration; and pallium development. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study Miller-Dieker lissencephaly syndrome and left ventricular noncompaction. Orthologous to human YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Ywhae 基因产物(1)

mRNA Protein Name
NM_009536.4 NP_033562.3 14-3-3 protein epsilon
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11585834 MGI
enables protein domain specific binding IDA
IDA: 通过直接分析推断
12446771 MGI
enables protein phosphatase binding IPI
IPI: 通过物理相互作用推断
23326474 MGI
enables protein phosphatase inhibitor activity IDA
IDA: 通过直接分析推断
12796778 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cerebral cortex development IMP
IMP: 通过突变表型推断
12796778 MGI
acts upstream of or within hippocampus development IMP
IMP: 通过突变表型推断
12796778 MGI
acts upstream of or within neuron migration IGI
IGI: 通过遗传相互作用推断
12796778 MGI
acts upstream of or within neuron migration IMP
IMP: 通过突变表型推断
12796778 MGI
acts upstream of or within protein targeting IDA
IDA: 通过直接分析推断
12446771 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
23326474 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

14-3-3 protein epsilon

14-3-3 epsilon

14-3-3E

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activatioprotein, epsilon polypeptide

重组 Ywhae 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75549 14-3-3 epsilon Protein, Mouse (His) P62259 (M1-Q255) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ywhae NCBI NCBI:7531