2. Gene
  3. Pcgf2 - polycomb group ring finger 2 Gene

Pcgf2 - polycomb group ring finger 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mel18; Rnf110; Zfp144; mel-18

基因 ID: 22658 | 基因类型: protein coding

关于 Pcgf2

功能概要

Enables chromatin binding activity. Acts upstream of or within several processes, including cellular response to hydrogen peroxide; chordate embryonic development; and negative regulation of apoptotic signaling pathway. Located in nuclear body and sex chromatin. Part of PcG protein complex. Is expressed in several structures, including adipose tissue; alimentary system; brain; eye; and genitourinary system. Orthologous to human PCGF2 (polycomb group ring finger 2). [provided by Alliance of Genome Resources, Apr 2022]

Pcgf2 基因产物(3)

mRNA Protein Name
NM_001163307.1 NP_001156779.1 polycomb group RING finger protein 2
NM_001163308.1 NP_001156780.1 polycomb group RING finger protein 2
NM_009545.2 NP_033571.1 polycomb group RING finger protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
15741318 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12034499 MGI
NOT enables ubiquitin-protein transferase activator activity IDA
IDA: 通过直接分析推断
16359901 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within anterior/posterior pattern specification IGI
IGI: 通过遗传相互作用推断
15741318 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: 通过突变表型推断
8625838 MGI
acts upstream of apoptotic signaling pathway IGI
IGI: 通过遗传相互作用推断
11290297 MGI
acts upstream of or within cellular response to hydrogen peroxide IDA
IDA: 通过直接分析推断
20808772 MGI
acts upstream of or within chromatin organization IGI
IGI: 通过遗传相互作用推断
16687444 MGI
acts upstream of or within embryonic skeletal system development IGI
IGI: 通过遗传相互作用推断
11290297 MGI
acts upstream of or within embryonic skeletal system morphogenesis IGI
IGI: 通过遗传相互作用推断
11290297 MGI
acts upstream of or within in utero embryonic development IGI
IGI: 通过遗传相互作用推断
11290297 MGI
acts upstream of or within negative regulation of apoptotic signaling pathway IGI
IGI: 通过遗传相互作用推断
11290297 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
11290297 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of PRC1 complex IDA
IDA: 通过直接分析推断
16359901 MGI
part of PcG protein complex IDA
IDA: 通过直接分析推断
28596365 MGI
located in nuclear body IDA
IDA: 通过直接分析推断
12183370 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12034499 MGI
located in sex chromatin IDA
IDA: 通过直接分析推断
15525528 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

polycomb group RING finger protein 2

DNA-binding protein Mel-18

melanoma nuclear protein 18

ring finger protein 110

zfp-144

zinc finger protein 144

Pcgf2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Pcgf2 P23798 Phc2 Mus musculus Q9QWH1
Anti Tag CoIP
22325148
种属内
Pcgf2 P23798 Phc2 Mus musculus Q9QWH1
Y2H
12183370
种属内
Pcgf2 P23798 Rnf2 Mus musculus Q9CQJ4
Anti Tag CoIP
22325148
种属内
Pcgf2 P23798 Rnf2 Mus musculus Q9CQJ4
IF
12183370
种属内
Pcgf2 P23798 Rnf2 Mus musculus Q9CQJ4
Y2H
12183370
种属内
Pcgf2 P23798 Rnf2 Mus musculus Q9CQJ4
Anti Bait CoIP
22325148
种属内
Pcgf2 P23798 Rnf2 Mus musculus Q9CQJ4
Anti Tag CoIP
16359901
种属内
Pcgf2 P23798 Rnf2 Mus musculus Q9CQJ4
Pull Down
12183370
种属内
Pcgf2 P23798 Phc1 Mus musculus Q64028
Y2H
12183370
种属内
Pcgf2 P23798 Phc1 Mus musculus Q64028
Anti Tag CoIP
22325148
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10146 PCGF2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pcgf2 NCBI NCBI:7703
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