1. Gene
  2. PHLDA1 - pleckstrin homology like domain family A member 1 Gene

PHLDA1 - pleckstrin homology like domain family A member 1 Gene

中文名称:pleckstrin 同源性样域家族 A 成员 1

种属: Homo sapiens

同用名: PHRIP; TDAG51; DT1P1B11

基因 ID: 22822 | 基因类型: protein coding

关于 PHLDA1

Cytogenetic location: 12q21.2 Genomic coordinates (GRCh38): 12:76,025,447-76,031,776 (from NCBI)

This gene has 3 transcripts (splice variants), 172 orthologues and 2 paralogues. Ubiquitous expression in salivary gland (RPKM 37.9), liver (RPKM 29.7) and 25 other tissues.

功能概要

该基因编码一种进化上保守的富含脯氨酸-组氨酸的核蛋白。编码的蛋白质可能在胰岛素样生长因子-1 的抗细胞凋亡作用中发挥重要作用。[RefSeq 提供,2008 年 7 月]

This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008]

PHLDA1 基因产物(1)

mRNA Protein Name
NM_007350.3 NP_031376.3 pleckstrin homology-like domain family A member 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11369516 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

pleckstrin homology-like domain family A member 1

PQ-rich protein

PHLDA1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PHLDA1 Q8WV24 EIF3D Homo sapiens O15371
Y2H
11369516
种属内
PHLDA1 Q8WV24 EIF3D Homo sapiens O15371 11369516
种属内
PHLDA1 Q8WV24 PABPC4 Homo sapiens Q13310 11369516
种属内
PHLDA1 Q8WV24 MDFI Homo sapiens Q99750 19060904
种属内
PHLDA1 Q8WV24 MDFI Homo sapiens Q99750 19060904
种属间: 跨种属相互作用 种属内: 同种属相互作用

PHLDA1 抗体

目录号 产品名 应用 反应物种
HY-P81871 PHLDA1 Antibody (YA1616) WB, IHC-F, IHC-P, ICC/IF Human

关联疾病

疾病名称 别名
Malignant Syringoma

Microcystic Adnexal Carcinoma

Microcystic Adnexal Carcinoma Of Skin

Syringomatous Carcinoma

Eccrine Epithelioma

Fibroepithelial Basal Cell Carcinoma

Fibroepithelioma Of Pinkus

Fibroepithelioma Of Pinkus Type

Pinkus Tumor

Inverted Follicular Keratosis

Inverted Folicular Keratosis

Seborrheic Keratosis

Malignant Acrospiroma

Eccrine Ductal Carcinoma

Hidradenocarcinoma

Anaplastic Syringoma

Eccrine Ductal Carcinoma Of Skin

Clear Cell Eccrine Carcinoma

Malignant Clear Cell Acrospiroma

Malignant Nodular/Clear Cell Hidradenoma

Primary Mucoepidermoid Cutaneous Carcinoma

Sweat Gland Adenocarcinoma

Follicular Infundibulum Tumor

Tumor Of Follicular Infundibulum

Follicular Infundibulum Tumour

Neoplasm Of The Follicular Infundibulum

Tumour Of Follicular Infundibulum

Morpheaform Basal Cell Carcinoma

Basal Cell Carcinoma, Morphea

Cicatricial Basal-Cell Carcinoma

Morphea-Type Basal Cell Carcinoma

Morpheic Basal Cell Carcinoma

Clear Cell Basal Cell Carcinoma

Skin Clear Cell Basal Cell Carcinoma

Basal Cell Carcinoma, Infundibulocystic

Basal Cell Carcinoma With Follicular Differentiation

Infundibulocystic Basal Cell Carcinoma

Skin Infundibulocystic Basal Cell Carcinoma

Pilar Sheath Acanthoma

Acanthoma, Pilar Sheath

Aggressive Digital Papillary Adenocarcinoma
Epidermal Appendage Tumor

Neoplasm Of Skin With Adnexal Differentiation

Neoplasm Of The Skin Appendage

Skin Appendage Tumour

Squamous Papillomatosis
Eccrine Sweat Gland Cancer

Malignant Eccrine Skin Neoplasm

Malignant Eccrine Tumor

Sweat Gland Cancer

Sweat Gland Carcinoma

Malignant Neoplasm Of Sweat Gland

Malignant Tumor Of The Sweat Gland

Carcinoma Of The Sweat Gland

Primary Malignant Neoplasm Of Sweat Gland

Sweat Gland Neoplasms

Hair Follicle Neoplasm

Hair Matrix Neoplasm

Hair Matrix Tumour

Syringocystadenoma Papilliferum

Fistulous Vegetative Verrucous Hydradenoma

Papillary Syringadenoma

Naevus Syringocystadenomatosus Papilliferus

Papillary Syringocystadenoma

Scap

Syringadenoma Papilliferum

Papillary Hidradenoma

Acanthoma
Hidrocystoma

Apocrine Cystadenoma

Eccrine Hidrocystoma

Eccrine Cystadenoma

Eccrine Hidrocystoma Of Skin

Apocrine Adenoma

Brooke-Spiegler Syndrome

Cyld Cutaneous Syndrome

Spiegler-Brooke Syndrome

Familial Cylindromatosis

BRSS

Bss

Sbs

Multiple Familial Trichoepithelioma

Ancell-Spiegler Cylindromas

Familial Multiple Trichoepithelioma

Trichoepithelioma

Fc

Mft

Multiple Familial Trichoepitheliomas

Ccs

Turban Tumor Syndrome

Schilbach-Rott Syndrome

Eccrine Dermal Cylindroma

Familial Multiple Trichoepitheliomata

Hidradenoma

Adenoma, Sweat Gland

Hidradenoma Of Skin

Sweat Gland Adenoma

Syringoadenoma

Eccrine Acrospiroma

Benign Neoplasm Of Sweat Gland

Eccrine Papillary Adenocarcinoma

Digital Papillary Adenocarcinoma

Sweat Gland Adenocarcinoma

Digital Papillary Eccrine Carcinoma Of Skin

Basosquamous Carcinoma

Carcinoma, Basosquamous

Basisquamous Cell Carcinoma

Basosquamous Cell Carcinoma

Metatypical Carcinoma

Pilomatrixoma

Pilomatricoma

PTR

Epithelioma Calcificans Of Malherbe

Benign Pilomatricoma

Calcifying Epithelioma Of Malherbe

Pilomatricoma, Somatic

Benign Pilomatrixoma

Malherbe Calcifying Epithelioma

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus PHLDA1 VGNC VGNC:68830
Rattus norvegicus PHLDA1 RGD RGD:3836
Mus musculus PHLDA1 MGD MGI:1096880
Bos taurus PHLDA1 VGNC VGNC:32835
Canis familiaris PHLDA1 VGNC VGNC:44501