2. Gene
  3. Mavs - mitochondrial antiviral signaling protein Gene

Mavs - mitochondrial antiviral signaling protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Visa; IPS-1; cardif; D430028G21Rik

基因 ID: 228607 | 基因类型: protein coding

关于 Mavs

功能概要

Enables signaling adaptor activity. Involved in several processes, including negative regulation of viral genome replication; positive regulation of myeloid dendritic cell cytokine production; and regulation of peroxisome organization. Acts upstream of or within RIG-I signaling pathway; positive regulation of defense response to virus by host; and positive regulation of type I interferon production. Located in mitochondrion and peroxisome. Orthologous to human MAVS (mitochondrial Antiviral signaling protein). [provided by Alliance of Genome Resources, Apr 2022]

Mavs 基因产物(4)

mRNA Protein Name
NM_001206382.1 NP_001193311.1 mitochondrial antiviral-signaling protein isoform 2
NM_001206383.1 NP_001193312.1 mitochondrial antiviral-signaling protein isoform 2
NM_001206385.1 NP_001193314.1 mitochondrial antiviral-signaling protein isoform 1
NM_144888.2 NP_659137.1 mitochondrial antiviral-signaling protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16858409 MGI
enables signaling adaptor activity IDA
IDA: 通过直接分析推断
23582325 MGI
enables signaling adaptor activity IMP
IMP: 通过突变表型推断
20451243 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within RIG-I signaling pathway IGI
IGI: 通过遗传相互作用推断
22745163 MGI
involved in negative regulation of viral genome replication IMP
IMP: 通过突变表型推断
20451243 MGI
involved in positive regulation of NLRP3 inflammasome complex assembly IDA
IDA: 通过直接分析推断
23582325 MGI
acts upstream of or within positive regulation of defense response to virus by host IMP
IMP: 通过突变表型推断
18780793 MGI
acts upstream of or within positive regulation of interferon-alpha production IMP
IMP: 通过突变表型推断
31390091 MGI
acts upstream of or within positive regulation of interferon-beta production IMP
IMP: 通过突变表型推断
31390091 MGI
acts upstream of or within positive regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
31390091 MGI
involved in positive regulation of myeloid dendritic cell cytokine production IMP
IMP: 通过突变表型推断
21703541 MGI
acts upstream of or within positive regulation of type I interferon production IMP
IMP: 通过突变表型推断
18780793 MGI
involved in protein localization to mitochondrion IDA
IDA: 通过直接分析推断
23582325 MGI
involved in regulation of peroxisome organization IMP
IMP: 通过突变表型推断
20451243 MGI
involved in signal transduction IMP
IMP: 通过突变表型推断
20451243 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
20451243 MGI
located in peroxisome IDA
IDA: 通过直接分析推断
20451243 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mitochondrial antiviral-signaling protein

CARD adapter inducing interferon beta

IFN-beta promoter stimulator-1

interferon beta promoter stimulator protein 1

mitochondrial anti-viral signaling protein

virus-induced signaling adapter

Mavs 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Mavs Q8VCF0 Traf3 Mus musculus Q60803
Anti Bait CoIP
16858409
种属内
Mavs Q8VCF0 Traf3 Mus musculus Q60803
Pull Down
16858409
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-123805 KIN1400 98.1% 否
HY-RS08176 MAVS Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-113687 T145 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mavs NCBI NCBI:57506
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