KHDC4 - KH domain containing 4, pre-mRNA splicing factor Gene

中文名称：含 KH 结构域 4 个 pre-mRNA 剪接因子

种属: Homo sapiens

同用名: BLOM7; KIAA0907; SNORA80EHG

基因 ID: 22889 | 基因类型: protein coding

关于 KHDC4

Cytogenetic location: 1q22 Genomic coordinates (GRCh38): 1:155,913,045-155,934,413 (from NCBI)

This gene has 10 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in lymph node (RPKM 16.6), spleen (RPKM 15.4) and 25 other tissues.

功能概要

启用 RNA 结合活性。参与 mRNA 剪接位点选择。位于细胞质和核质中。与剪接体复合体共定位。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Involved in mRNA splice site selection. Located in cytoplasm and nucleoplasm. Colocalizes with spliceosomal complex. [provided by Alliance of Genome Resources, Apr 2022]

KHDC4 基因产物(1)

mRNA	Protein	Name
NM_014949.4	NP_055764.2	KH homology domain-containing protein 4

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables RNA binding	IDA IDA: 通过直接分析推断	19641227	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	19641227	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in mRNA splice site recognition	IDA IDA: 通过直接分析推断	19641227	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	19641227	GOA
located in nucleus	IDA IDA: 通过直接分析推断	19641227	GOA
part of spliceosomal complex	IDA IDA: 通过直接分析推断	19641227	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

KH homology domain-containing protein 4

brings lots of money 7

KHDC4 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	KHDC4	Q7Z7F0	RBM39	Homo sapiens	Q14498-3	Y2H Prey Pooling	25416956
种属内	KHDC4	Q7Z7F0	RBM39	Homo sapiens	Q14498-3	Validated Y2H	25416956
种属内	KHDC4	Q7Z7F0	RBM39	Homo sapiens	Q14498-3	Y2H Array	25416956
种属内	KHDC4	Q7Z7F0	SF1	Homo sapiens	Q15637	Y2H Fragment Pooling	26420826

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Lip Cancer

Malignant Neoplasm Of Lip	Malignant Neoplasm Of Oral Aspect Of Lip, Not Specified Whether Upper Or Lower
Malignant Tumour Of Lip	Lip Neoplasms
Malignant Neoplasm Of Commissure Of Lip	Malignant Neoplasm Of External Lip, Not Specified As Upper Or Lower
Malignant Neoplasm Of Labial Commissure Of Lip	Malignant Neoplasm Of Lip, External
Malignant Neoplasm Of Lip, Inner Aspect	Malignant Neoplasm Of Lip, Vermilion Border
Malignant Neoplasm Of Lower Lip, Buccal Aspect	Malignant Neoplasm Of Lower Lip, Inner Aspect
Malignant Neoplasm Of Lower Lip, Mucosa	Malignant Neoplasm Of Lower Lip, Oral Aspect
Malignant Neoplasm Of Other Sites Of Lip	Malignant Neoplasm Of Vermilion Border Of Lip
Malignant Tumor Of Commissure Of Lip	Malignant Tumor Of Labial Mucosa
Malignant Tumor Of Lip	Malignant Tumor Of Lower Labial Mucosa
Malignant Tumor Of The Lip	Malignant Tumour Of Labial Commissure
Cancer Of Lip	Primary Malignant Neoplasm Of Vermilion Border Of Upper Lip
Upper Lip Cancer	Lower Lip Cancer
Primary Malignant Neoplasm Of Vermilion Border Of Lower Lip	Primary Malignant Neoplasm Of Vermilion Border Of Lip
Malignant Neoplasm Of Lipstick Area Of Upper Lip	Malignant Neoplasm Of Upper Lip Nos
Malignant Neoplasm Of Vermilion Border Of Upper Lip	Malignant Neoplasm Of Lipstick Area Of Lower Lip
Malignant Neoplasm Of Lower Lip Nos	Malignant Neoplasm Of Vermilion Border Of Lower Lip
Malignant Neoplasm Of Vermilion Border Nos	Malignant Neoplasm Of Buccal Aspect Of Upper Lip
Malignant Neoplasm Of Frenulum Of Upper Lip	Malignant Neoplasm Of Mucosa Of Upper Lip
Malignant Neoplasm Of Oral Aspect Of Upper Lip	Malignant Neoplasm Of Buccal Aspect Of Lower Lip
Malignant Neoplasm Of Frenulum Of Lower Lip	Malignant Neoplasm Of Mucosa Of Lower Lip
Malignant Neoplasm Of Oral Aspect Of Lower Lip	Malignant Neoplasm Of Buccal Aspect Of Lip, Not Specified Whether Upper Or Lower
Malignant Neoplasm Of Frenulum Of Lip, Not Specified Whether Upper Or Lower	Malignant Neoplasm Of Mucosa Of Lip, Not Specified Whether Upper Or Lower
Primary Malignant Neoplasm Of Commissure Of Lip	Primary Malignant Neoplasm Of Lip
Malignant Neoplasm Of Lip, Unspecified

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS07236	KHDC4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	KHDC4	VGNC	VGNC:63077
Macaca mulatta	KHDC4	VGNC	VGNC:73931
Canis familiaris	KHDC4	VGNC	VGNC:42354
Mus musculus	KHDC4	MGD	MGI:1921450
Bos taurus	KHDC4	VGNC	VGNC:30559
Rattus norvegicus	KHDC4	RGD	RGD:1565775

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

KHDC4 - KH domain containing 4, pre-mRNA splicing factor Gene

关于 KHDC4

功能概要

KHDC4 基因产物(1)

KHDC4 蛋白互作信息

关联疾病

直系同源

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KHDC4 - KH domain containing 4, pre-mRNA splicing factor Gene

关于 KHDC4

功能概要

KHDC4 基因产物(1)

KHDC4 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z