2. Gene
  3. STK38L - serine/threonine kinase 38 like Gene

STK38L - serine/threonine kinase 38 like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：丝氨酸/苏氨酸激酶 38 样

种属: Homo sapiens

同用名: NDR2

基因 ID: 23012 | 基因类型: protein coding

关于 STK38L

Cytogenetic location: 12p11.23 Genomic coordinates (GRCh38): 12:27,244,286-27,325,959 (from NCBI)

This gene has 13 transcripts (splice variants), 216 orthologues and 1 paralogue. Ubiquitous expression in gall bladder (RPKM 16.1), heart (RPKM 15.2) and 25 other tissues.

功能概要

启用 ATP 绑定活动；镁离子结合活性；和蛋白丝氨酸/苏氨酸激酶活性。参与细胞内信号转导。作用于蛋白质磷酸化的上游或内部。位于胞质溶胶中。 [由基因组资源联盟提供，2022 年 4 月]

Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in intracellular signal transduction. Acts upstream of or within protein phosphorylation. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

STK38L 基因产物(1)

mRNA Protein Name
NM_015000.4 NP_055815.1 serine/threonine-protein kinase 38-like
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
15067004 GOA
enables magnesium ion binding IDA
IDA: 通过直接分析推断
15067004 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
15197186 GOA
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
15037617 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular signal transduction IDA
IDA: 通过直接分析推断
15067004 GOA
involved in negative regulation of autophagy IDA
IDA: 通过直接分析推断
35670107 GOA
acts upstream of or within protein phosphorylation IDA
IDA: 通过直接分析推断
15037617 GOA
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
15067004 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15037617 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

STK38L 蛋白结构

Pkinase

Pkinase: Protein kinase domain (91 - 383)

Pkinase_C

Pkinase_C: Protein kinase C terminal domain (402 - 446)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 464 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase 38-like

NDR2 protein kinase

STK38L 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
STK38L Q9Y2H1 MOB2 Homo sapiens Q70IA6
Y2H Prey Pooling
32296183
种属内
STK38L Q9Y2H1 MOB2 Homo sapiens Q70IA6
Pull Down
30108113
种属内
STK38L Q9Y2H1 MOB2 Homo sapiens Q70IA6
Anti Tag CoIP
24366813
种属内
STK38L Q9Y2H1 MOB2 Homo sapiens Q70IA6
Anti Tag CoIP
35271311
种属内
STK38L Q9Y2H1 MOB2 Homo sapiens Q70IA6
Y2H Array
32296183
种属内
STK38L Q9Y2H1 MOB2 Homo sapiens Q70IA6
Anti Tag CoIP
33961781
种属内
STK38L Q9Y2H1 MOB2 Homo sapiens Q70IA6
Anti Tag CoIP
28514442
种属内
STK38L Q9Y2H1 MOB2 Homo sapiens Q70IA6
Anti Tag CoIP
25852190
种属内
STK38L Q9Y2H1 CDC37 Homo sapiens Q16543
BioID
30108113
种属内
STK38L Q9Y2H1 CDC37 Homo sapiens Q16543
Anti Tag CoIP
24366813
种属内
STK38L Q9Y2H1 CDC37 Homo sapiens Q16543
Pull Down
30108113
种属内
STK38L Q9Y2H1 MOB1A Homo sapiens Q9H8S9
Anti Bait CoIP
17353931
种属内
STK38L Q9Y2H1 MOB1A Homo sapiens Q9H8S9
Anti Tag CoIP
33961781
种属内
STK38L Q9Y2H1 MOB1A Homo sapiens Q9H8S9
Anti Tag CoIP
28514442
种属内
STK38L Q9Y2H1 MOB1A Homo sapiens Q9H8S9
Anti Tag CoIP
25852190
种属内
STK38L Q9Y2H1 MOB1A Homo sapiens Q9H8S9
Anti Tag CoIP
24366813
种属内
STK38L Q9Y2H1 MOB1A Homo sapiens Q9H8S9
Anti Tag CoIP
35271311
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Warburg Micro Syndrome 1

Warburg Micro Syndrome

Micro Syndrome

Warbm

WARBM1

Warburg Sjo Fledelius Syndrome

Warburg-Sjo-Fledelius Syndrome

Micro Syndrome 1

Microcephaly, Microcornea, Congenital Cataract, Intellectual Disability, Optic Atrophy And Hypogenitalism
Ossification Of The Posterior Longitudinal Ligament Of Spine

OPLL

Ossification Of The Posterior Longitudinal Ligament Of The Spine

Ossification Of Posterior Longitudinal Ligament Of Spine

Ossification, Posterior Longitudinal Ligament Spine
Warburg Micro Syndrome 3

WARBM3

Micro Syndrome 3
Warburg Micro Syndrome 2

WARBM2

Micro Syndrome 2
Diffuse Idiopathic Skeletal Hyperostosis

Hyperostosis, Diffuse Idiopathic Skeletal

Ankylosing Vertebral Hyperostosis

Dish

Disseminated Idiopathic Skeletal Hyperostosis

Forestier Disease

Forestier'S Disease

Hyperostosis Diffuse Idiopathic Skeletal
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13939 STK38L Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus STK38L VGNC VGNC:65787
Macaca mulatta STK38L VGNC VGNC:78156
Rattus norvegicus STK38L RGD RGD:1564793
Canis familiaris STK38L VGNC VGNC:46920
Mus musculus STK38L MGD MGI:1922250
Bos taurus STK38L VGNC VGNC:35400
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