2. Gene
  3. MOB2 - MOB kinase activator 2 Gene

MOB2 - MOB kinase activator 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：MOB 激酶激活因子 2

种属: Homo sapiens

同用名: HCCA2

基因 ID: 81532 | 基因类型: protein coding

关于 MOB2

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:1,469,448-1,486,779 (from NCBI)

This gene has 6 transcripts (splice variants), 223 orthologues and 6 paralogues. Ubiquitous expression in skin (RPKM 12.1), endometrium (RPKM 11.8) and 25 other tissues.

功能概要

预测可启用金属离子结合活性。预测作用于肌动蛋白细胞骨架组织的上游或内部；神经元投射发育的正向调节；和蛋白质磷酸化的正调节。位于胞质溶胶中；核仁;和核质。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable metal ion binding activity. Predicted to act upstream of or within actin Cytoskeleton organization; positive regulation of neuron projection development; and positive regulation of protein phosphorylation. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MOB2 基因产物(2)

mRNA Protein Name
NM_001172223.3 NP_001165694.1 MOB kinase activator 2 isoform 1
NM_053005.5 NP_443731.2 MOB kinase activator 2 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24366813 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MOB2 蛋白结构

Mob1_phocein

Mob1_phocein: Mob1/phocein family (64 - 230)

  • 0
  • 100
  • 200
  • 268 a.a.
蛋白主名 其他名称

MOB kinase activator 2

MOB2 Mps One Binder homolog

MOB2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MOB2 Q70IA6 RETREG3 Homo sapiens Q86VR2
Y2H Prey Pooling
32296183
种属内
MOB2 Q70IA6 RETREG3 Homo sapiens Q86VR2
Validated Y2H
32296183
种属内
MOB2 Q70IA6 RETREG3 Homo sapiens Q86VR2
Y2H Array
32296183
种属内
MOB2 Q70IA6 FAAP20 Homo sapiens Q6NZ36-4
Y2H Prey Pooling
32296183
种属内
MOB2 Q70IA6 FAAP20 Homo sapiens Q6NZ36-4
Y2H Array
32296183
种属内
MOB2 Q70IA6 OR5H1 Homo sapiens A6NKK0
Y2H Prey Pooling
32296183
种属内
MOB2 Q70IA6 OR5H1 Homo sapiens A6NKK0
Y2H Array
32296183
种属内
MOB2 Q70IA6 MIIP Homo sapiens Q5JXC2
Y2H Prey Pooling
32296183
种属内
MOB2 Q70IA6 MIIP Homo sapiens Q5JXC2
Y2H Array
32296183
种属内
MOB2 Q70IA6 SFT2D2 Homo sapiens O95562
Y2H Prey Pooling
32296183
种属内
MOB2 Q70IA6 SFT2D2 Homo sapiens O95562
Validated Y2H
32296183
种属内
MOB2 Q70IA6 SFT2D2 Homo sapiens O95562
Y2H Array
32296183
种属内
MOB2 Q70IA6 STK38 Homo sapiens Q15208
Anti Tag CoIP
33961781
种属内
MOB2 Q70IA6 FRA10AC1 Homo sapiens Q70Z53
Y2H Prey Pooling
32296183
种属内
MOB2 Q70IA6 FRA10AC1 Homo sapiens Q70Z53
Validated Y2H
32296183
种属内
MOB2 Q70IA6 FRA10AC1 Homo sapiens Q70Z53
Y2H Array
32296183
种属内
MOB2 Q70IA6 CCDC90B Homo sapiens Q9GZT6
Validated Y2H
32296183
种属内
MOB2 Q70IA6 CCDC90B Homo sapiens Q9GZT6
Y2H Array
32296183
种属内
MOB2 Q70IA6 CCDC90B Homo sapiens Q9GZT6
Y2H Prey Pooling
32296183
种属内
MOB2 Q70IA6 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
种属内
MOB2 Q70IA6 ATG3 Homo sapiens Q9NT62
Validated Y2H
32296183
种属内
MOB2 Q70IA6 ATG3 Homo sapiens Q9NT62
Y2H Array
32296183
种属内
MOB2 Q70IA6 ATG3 Homo sapiens Q9NT62
Y2H Prey Pooling
32296183
种属内
MOB2 Q70IA6 STK38L Homo sapiens Q9Y2H1
Anti Tag CoIP
33961781
种属内
MOB2 Q70IA6 STK38L Homo sapiens Q9Y2H1
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Van Maldergem Syndrome

Van Maldergem Wetzburger Verloes Syndrome

Cerebro-Facio-Articular Syndrome

Cerebro-Facio-Articular Syndrome Of Van Maldergem

Cerebrofacioarticular Syndrome

Cerebro Facio Articular Syndrome

Van Maldergem-Wetzburger-Verloes Syndrome
Periventricular Nodular Heterotopia

Periventricular Heterotopia

Pvnh

Familial Nodular Heterotopia

Heterotopia, Periventricular

Periventricular Heterotopia, X-Linked
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08575 MOB2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta MOB2 VGNC VGNC:101353
Felis catus MOB2 VGNC VGNC:63545
Mus musculus MOB2 MGD MGI:1919891
Bos taurus MOB2 VGNC VGNC:31543
Canis familiaris MOB2 VGNC VGNC:43301
Rattus norvegicus MOB2 RGD RGD:1562983
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z