2. Gene
  3. MDN1 - midasin AAA ATPase 1 Gene

MDN1 - midasin AAA ATPase 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：咪达辛 AAA ATP 酶 1

种属: Homo sapiens

同用名: Rea1

基因 ID: 23195 | 基因类型: protein coding

关于 MDN1

Cytogenetic location: 6q15 Genomic coordinates (GRCh38): 6:89,642,498-89,819,794 (from NCBI)

This gene has 28 transcripts (splice variants), 1 gene allele, 209 orthologues and 3 paralogues. Ubiquitous expression in ovary (RPKM 5.6), testis (RPKM 4.9) and 25 other tissues.

功能概要

预测启用 ATP 绑定活动。参与核糖体大亚基组装。位于胞质溶胶中；中间丝细胞骨架；和核腔。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity. Involved in ribosomal large subunit assembly. Located in cytosol; intermediate filament cytoskeleton; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

MDN1 基因产物(1)

mRNA Protein Name
NM_014611.3 NP_055426.1 midasin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21326211 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ribosomal large subunit assembly IDA
IDA: 通过直接分析推断
27814492 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
27814492 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MDN1 蛋白结构

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (325 - 452)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (672 - 768)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (816 - 902)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (1079 - 1215)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (1385 - 1540)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (1749 - 1888)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (2062 - 2106)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (2219 - 2300)

  • 0
  • 900
  • 1800
  • 2700
  • 3600
  • 4500
  • 5596 a.a.
蛋白主名 其他名称

midasin

MDN1, midasin homolog

MDN1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MDN1 Q9NU22 PELP1 Homo sapiens Q8IZL8
Anti Bait CoIP
21326211
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Acute Apical Periodontitis

Acute Apical Periodontitis Of Pulpal Origin

Acute Apical Periodontitis Nos

Aap - [Acute Apical Periodontitis]
Ewing Sarcoma Of Bone

Ewing'S Sarcoma Of Bone

Bone Ewing Sarcoma

Bone Ewing'S Sarcoma

Bone Localized Ewing Sarcoma

Bone Localized Ewing'S Sarcoma

Ewing'S Sarcoma/Bone Peripheral Primitive Neuroectodermal Tumor

Localized Skeletal Ewing'S Sarcoma

Localized Bone Ewing Sarcoma
Plasmodium Ovale Malaria

Ovale Malaria

Malariaby Plasmodium Ovale
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100816 Rbin-1 Inhibitor 99.85% 否
HY-100817 Rbin-2 Inhibitor ≥98.0% 否
HY-RS08268 MDN1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus MDN1 MGD MGI:1926159
Macaca mulatta MDN1 VGNC VGNC:74530
Bos taurus MDN1 VGNC VGNC:31338
Canis familiaris MDN1 VGNC VGNC:43108
Rattus norvegicus MDN1 RGD RGD:1306394
Felis catus MDN1 VGNC VGNC:102458
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