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  3. TASOR - transcription activation suppressor Gene

TASOR - transcription activation suppressor Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：转录激活抑制因子

种属: Homo sapiens

同用名: RAP140; TASOR1; se89-1; C3orf63; FAM208A

基因 ID: 23272 | 基因类型: protein coding

关于 TASOR

Cytogenetic location: 3p14.3 Genomic coordinates (GRCh38): 3:56,620,132-56,683,265 (from NCBI)

This gene has 11 transcripts (splice variants), 266 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 15.9), lymph node (RPKM 11.5) and 25 other tissues.

功能概要

启用染色质结合活性。通过双链 DNA 中间体参与单链病毒 RNA 复制的负调控；蛋白质定位于异染色质；和基因表达的调控。位于异染色质和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables chromatin binding activity. Involved in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; protein localization to heterochromatin; and regulation of gene expression. Located in heterochromatin and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TASOR 基因产物(7)

mRNA Protein Name
NM_001112736.2 NP_001106207.1 protein TASOR isoform a
NM_001363940.1 NP_001350869.1 protein TASOR isoform c
NM_001365635.2 NP_001352564.1 protein TASOR isoform d
NM_001365636.2 NP_001352565.1 protein TASOR isoform e
NM_001365637.2 NP_001352566.1 protein TASOR isoform f
NM_001365638.2 NP_001352567.1 protein TASOR isoform g
NM_015224.3 NP_056039.2 protein TASOR isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
29211708 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
26022416 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of gene expression, epigenetic IDA
IDA: 通过直接分析推断
26022416 GOA
involved in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate IMP
IMP: 通过突变表型推断
29211708 GOA
involved in positive regulation of DNA methylation-dependent heterochromatin formation IDA
IDA: 通过直接分析推断
28581500 GOA
involved in protein localization to heterochromatin IDA
IDA: 通过直接分析推断
28581500 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in heterochromatin IDA
IDA: 通过直接分析推断
28581500 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TASOR 蛋白结构

DUF3715

DUF3715: Protein of unknown function (DUF3715) (151 - 319)

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  • 1512 a.a.
蛋白主名 其他名称

protein TASOR

CTCL tumor antigen se89-1

TASOR 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TASOR Q9UK61 MPHOSPH8 Homo sapiens Q99549
Anti Bait CoIP
26022416
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Retinitis Pigmentosa 75

RP75

Retinitis Pigmentosa, Type 75
Charcot-Marie-Tooth Disease

Cmt

Hmsn

Hereditary Motor And Sensory Neuropathy

Pma

Cmt - Charcot-Marie-Tooth Disease

Charcot Marie Tooth Disease

Charcot-Marie-Tooth Hereditary Neuropathy

Charcot-Marie-Tooth Syndrome

Peroneal Muscular Atrophy

Hereditary Motor And Sensory Neuropathies
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14222 TASOR Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS14223 TASOR2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TASOR VGNC VGNC:28783
Felis catus TASOR VGNC VGNC:65962
Mus musculus TASOR MGD MGI:1921694
Canis familiaris TASOR VGNC VGNC:40652
Rattus norvegicus TASOR RGD RGD:1595469
Macaca mulatta TASOR VGNC VGNC:78243
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