NCAPH - non-SMC condensin I complex subunit H Gene

中文名称：非 SMC 凝聚素 I 复合亚基 H

种属: Homo sapiens

同用名: CAPH; BRRN1; CAP-H; MCPH23

关于 NCAPH

功能概要

该基因编码 barr 基因家族的一个成员和凝缩蛋白复合物的一个调节亚基。该复合物是将间期染色质转化为浓缩染色体所必需的。由该基因编码的蛋白质与有丝分裂染色体有关，但在染色体浓缩的早期阶段除外。在间期，蛋白质具有明显的点状核仁定位。已经描述了编码不同蛋白质的可变剪接转录物变体。[RefSeq 提供，2013 年 7 月]

This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013]