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  3. Mta2 - metastasis-associated gene family, member 2 Gene

Mta2 - metastasis-associated gene family, member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: mmta2; Mta1l1; Mata1l1

基因 ID: 23942 | 基因类型: protein coding

关于 Mta2

功能概要

Enables histone deacetylase activity and transcription coregulator activity. Involved in negative regulation of transcription, DNA-templated. Acts upstream of or within DNA methylation; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of NuRD complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; limb; and retina. Used to study systemic lupus erythematosus. Orthologous to human MTA2 (metastasis associated 1 family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Mta2 基因产物(3)

mRNA Protein Name
NM_001412946.1 NP_001399875.1 metastasis-associated protein MTA2 isoform 2
NM_001412948.1 NP_001399877.1 metastasis-associated protein MTA2 isoform 2
NM_011842.4 NP_035972.3 metastasis-associated protein MTA2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone deacetylase activity IDA
IDA: 通过直接分析推断
10444591 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11836251 MGI
enables transcription coregulator activity IDA
IDA: 通过直接分析推断
20636338 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within genomic imprinting IMP
IMP: 通过突变表型推断
20720167 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
20636338 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11749719 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11749719 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of NuRD complex IDA
IDA: 通过直接分析推断
14645126 MGI
part of NuRD complex IPI
IPI: 通过物理相互作用推断
16462733 MGI
part of histone deacetylase complex IDA
IDA: 通过直接分析推断
10444591 MGI
located in nucleus IDA
IDA: 通过直接分析推断
11749719 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

metastasis-associated protein MTA2

metastais-associated gene family, member 2

metastasis-associated 1-like 1

metastasis-associated protein 2

Mta2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Mta2 Q9R190 Pou5f1 Mus musculus P20263
Anti Bait CoIP
20362541
种属内
Mta2 Q9R190 Sall4 Mus musculus Q8BX22
Anti Bait CoIP
20362541
种属内
Mta2 Q9R190 Esrrb Mus musculus Q61539
Anti Bait CoIP
20362541
种属内
Mta2 Q9R190 Hdac1 Mus musculus O09106
Anti Bait CoIP
20404188
种属内
Mta2 Q9R190 Hdac1 Mus musculus O09106
Anti Bait CoIP
24240174
种属内
Mta2 Q9R190 Hdac1 Mus musculus O09106
Anti Bait CoIP
19424149
种属内
Mta2 Q9R190 Hdac2 Mus musculus P70288
Anti Bait CoIP
24240174
种属内
Mta2 Q9R190 Hdac2 Mus musculus P70288
Anti Bait CoIP
19424149
种属内
Mta2 Q9R190 Hdac2 Mus musculus P70288
Anti Bait CoIP
20404188
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08747 MTA2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mta2 NCBI NCBI:9219
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