2. Gene
  3. Tiam2 - T cell lymphoma invasion and metastasis 2 Gene

Tiam2 - T cell lymphoma invasion and metastasis 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: STEF; mKIAA2016; 3000002F19Rik

基因 ID: 24001 | 基因类型: protein coding

关于 Tiam2

功能概要

Enables GTPase activator activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in activation of GTPase activity; positive regulation of axonogenesis; and small GTPase mediated signal transduction. Located in cytoplasm and membrane. Is expressed in several structures, including cartilage; central nervous system; genitourinary system; liver; and respiratory system. Orthologous to human TIAM2 (TIAM Rac1 associated GEF 2). [provided by Alliance of Genome Resources, Apr 2022]

Tiam2 基因产物(4)

mRNA Protein Name
NM_001122998.1 NP_001116470.1 rho guanine nucleotide exchange factor TIAM2 isoform 1
NM_001286757.1 NP_001273686.1 rho guanine nucleotide exchange factor TIAM2 isoform 2
NM_001286758.1 NP_001273687.1 rho guanine nucleotide exchange factor TIAM2 isoform 3
NM_011878.2 NP_036008.2 rho guanine nucleotide exchange factor TIAM2 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase activator activity IDA
IDA: 通过直接分析推断
11707441 MGI
enables guanyl-nucleotide exchange factor activity IDA
IDA: 通过直接分析推断
10364228 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10364228 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
11707441 MGI
located in membrane IDA
IDA: 通过直接分析推断
11707441 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

rho guanine nucleotide exchange factor TIAM2

T-lymphoma invasion and metastasis-inducing protein 2

RAS-related C3 botulinum substrate 1, guanine nucleotide exchange factor 1

SIF and TIAM1-like exchange factor

T-cell lymphoma invasion and metastasis 2

RAS-related C3 botulinum substrate 1, guanine nucleotide exchange factor 1

TIAM-2

Tiam2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Tiam2 Q6ZPF3 Cd44 Mus musculus P15379
SPR
19893486
种属间
Tiam2 Q6ZPF3 PARD3 Homo sapiens Q8TEW0-2
SPR
19893486
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14516 TIAM2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tiam2 NCBI NCBI:26230
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