1. Gene
  2. Hgf - hepatocyte growth factor Gene

Hgf - hepatocyte growth factor Gene

种属: Rattus norvegicus

同用名: HPTA

基因 ID: 24446 | 基因类型: protein coding

关于 Hgf

功能概要

Enables growth factor activity. Involved in several processes, including animal organ regeneration; positive regulation of angiogenesis; and positive regulation of myelination. Located in extracellular space. Used to study brain infarction. Biomarker of cholangiocarcinoma. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autosomal recessive nonsyndromic deafness 39; eye disease (multiple); neuropathy (multiple); and scleroderma (multiple). Orthologous to human HGF (hepatocyte growth factor). [provided by Alliance of Genome Resources, Apr 2022]

Hgf 基因产物(1)

mRNA Protein Name
NM_017017.2 NP_058713.1 hepatocyte growth factor preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables growth factor activity IMP
IMP: 通过突变表型推断
1826679 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
1826679 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
19638569 RGD
involved in negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
16885537 RGD
involved in positive regulation of angiogenesis IDA
IDA: 通过直接分析推断
17549731 RGD
involved in positive regulation of myelination IDA
IDA: 通过直接分析推断
17549731 RGD
involved in positive regulation of neuron projection regeneration IDA
IDA: 通过直接分析推断
17549731 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
19638569 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

hepatocyte growth factor

SF

hepatopoeitin-A

hepatopoietin-A

scatter factor

重组 Hgf 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71688 HGF Protein, Rat (GST) P17945 (T477-L728) ≥95%
HY-P73101 HGF Protein, Rat (HEK293) NP_058713.1 (Q33-L728) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hgf NCBI NCBI:3082
Canis familiaris Hgf NCBI NCBI:403441
Macaca fascicularis Hgf NCBI NCBI:102133907
Mus musculus Hgf NCBI NCBI:15234
Macaca mulatta Hgf NCBI NCBI:708316