1. Gene
  2. Il27 - interleukin 27 Gene

Il27 - interleukin 27 Gene

种属: Mus musculus

同用名: p28; Il30; IL-27; IL27-A; IL-27-A; IL-27p28

基因 ID: 246779 | 基因类型: protein coding

关于 Il27

功能概要

Enables interleukin-27 receptor binding activity. Acts upstream of or within positive regulation of defense response to virus by host and regulation of T cell proliferation. Located in extracellular space. Is expressed in decidua; embryo; and extraembryonic component. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and pulmonary tuberculosis. Orthologous to human IL27 (interleukin 27). [provided by Alliance of Genome Resources, Apr 2022]

Il27 基因产物(1)

mRNA Protein Name
NM_145636.2 NP_663611.1 interleukin-27 subunit alpha precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables interleukin-27 receptor binding IDA
IDA: 通过直接分析推断
12121660 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12121660 MGI
enables signaling receptor binding IDA
IDA: 通过直接分析推断
12121660 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of defense response to virus by host IDA
IDA: 通过直接分析推断
25268627 MGI
acts upstream of or within positive regulation of defense response to virus by host IGI
IGI: 通过遗传相互作用推断
25268627 MGI
acts upstream of or within regulation of T cell proliferation IDA
IDA: 通过直接分析推断
12121660 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
12121660 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

interleukin-27 subunit alpha

IL-27 p28 subunit

IL-27 subunit alpha

interleukin 30

重组 Il27 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72554 IL-27 Protein, Mouse (HEK293, His) O35228 (Y19-P228) & Q8K3I6 (F29-S234) ≥95%
HY-P73200 IL-27 Protein, Mouse (228a.a, HEK293, His) O35228 (Y19-P228) &GSGSGGSGGSGSGKL& Q8K3I6 (F29-S234) ≥95%
HY-P700206AF Animal-Free IL-30/IL-27A Protein, Mouse (His) Q8K3I6 (F29-S234) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il27 NCBI NCBI:246778