1. Gene
  2. Reg1a - regenerating family member 1 alpha Gene

Reg1a - regenerating family member 1 alpha Gene

种属: Rattus norvegicus

同用名: Reg; RGPI; Reg1; Rgp1; LITHOST; RATRGPI; RATLITHOST

基因 ID: 24714 | 基因类型: protein coding

关于 Reg1a

功能概要

Enables growth factor activity; identical protein binding activity; and protein Phosphatase binding activity. Involved in several processes, including animal organ regeneration; cellular response to gastrin; and positive regulation of epithelial cell proliferation. Located in several cellular components, including dendrite membrane; neuronal cell body membrane; and zymogen granule. Part of protein-containing complex. Biomarker of colon Cancer and myocardial infarction. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to several human genes including REG1A (regenerating family member 1 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Reg1a 基因产物(1)

mRNA Protein Name
NM_012641.2 NP_036773.1 lithostathine precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables growth factor activity IDA
IDA: 通过直接分析推断
10526060 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
11278730 RGD
enables phosphatase binding IPI
IPI: 通过物理相互作用推断
18929742 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10662590 RGD
enables protein phosphatase binding IPI
IPI: 通过物理相互作用推断
18929742 RGD
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
10753861 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to chemokine IEP
IEP: 通过表达模式推断
11113082 RGD
involved in cellular response to gastrin IEP
IEP: 通过表达模式推断
10348814 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
19284990 RGD
involved in midgut development IEP
IEP: 通过表达模式推断
7720628 RGD
involved in negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
18929742 RGD
involved in pancreas regeneration IEP
IEP: 通过表达模式推断
1985964 RGD
involved in positive regulation of acinar cell proliferation IDA
IDA: 通过直接分析推断
9788538 RGD
involved in positive regulation of dendrite extension IMP
IMP: 通过突变表型推断
22158612 RGD
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
18929742 RGD
involved in positive regulation of type B pancreatic cell proliferation IMP
IMP: 通过突变表型推断
24055447 RGD
involved in response to gastrin IEP
IEP: 通过表达模式推断
9834276 RGD
involved in response to growth hormone-releasing hormone IEP
IEP: 通过表达模式推断
7720628 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
24055447 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
1985964 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
16874863 RGD
involved in response to water-immersion restraint stress IEP
IEP: 通过表达模式推断
8698224 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basal part of cell IDA
IDA: 通过直接分析推断
12764608 RGD
located in dendrite membrane IDA
IDA: 通过直接分析推断
22158612 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
1886885 RGD
located in growth cone IDA
IDA: 通过直接分析推断
22158612 RGD
located in neuronal cell body membrane IDA
IDA: 通过直接分析推断
22158612 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
22158612 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
11278730 RGD
located in zymogen granule IDA
IDA: 通过直接分析推断
12764608 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lithostathine

ICRF

PSP

PTP

islet cells regeneration factor

islet of Langerhans regenerating protein

pancreatic stone protein

pancreatic thread protein

regenerating islet-derived 1 alpha

regenerating islet-derived mouse homolog 1

regeneration protein, lithostat

重组 Reg1a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77173 REG1A Protein, Rat (HEK293, Fc) P10758 (Q22-A165) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Reg1a NCBI NCBI:5967
Macaca fascicularis Reg1a NCBI