2. Gene
  3. Slc9a3 - solute carrier family 9 member A3 Gene

Slc9a3 - solute carrier family 9 member A3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Nhe3

基因 ID: 24784 | 基因类型: protein coding

关于 Slc9a3

功能概要

Enables sodium:proton antiporter activity. Involved in several processes, including regulation of pH; response to glucocorticoid; and sodium ion transport. Located in apical plasma membrane and brush border membrane. Used to study hypertension. Biomarker of obesity and renovascular hypertension. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 8. Orthologous to human SLC9A3 (solute carrier family 9 member A3). [provided by Alliance of Genome Resources, Apr 2022]

Slc9a3 基因产物(2)

mRNA Protein Name
NM_001414040.1 NP_001400969.1 sodium/hydrogen exchanger 3 precursor
NM_012654.3 NP_036786.2 sodium/hydrogen exchanger 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12576672 RGD
enables sodium:proton antiporter activity IDA
IDA: 通过直接分析推断
11880335 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian rhythm IEP
IEP: 通过表达模式推断
15780093 RGD
involved in receptor-mediated endocytosis IMP
IMP: 通过突变表型推断
15113744 RGD
involved in regulation of pH IDA
IDA: 通过直接分析推断
15265811 RGD
involved in regulation of sodium ion transport IMP
IMP: 通过突变表型推断
15238256 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
17095646 RGD
involved in sodium ion transport IDA
IDA: 通过直接分析推断
11880335 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
12907430 RGD
located in brush border IDA
IDA: 通过直接分析推断
11880335 RGD
located in brush border membrane IDA
IDA: 通过直接分析推断
15238256 RGD
located in recycling endosome membrane IDA
IDA: 通过直接分析推断
9442041 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sodium/hydrogen exchanger 3

NHE-3

Na(+)/H(+) exchanger 3

Solute carrier family 9 (sodium/hydrogen exchanger 3), antiporter 3, Na+/H+ (amiloride insensitive)

plasma membrane ion transport protein

solute carrier family 9 (sodium/hydrogen exchanger), member 3

solute carrier family

Slc9a3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra Slc9a3 P26433 Arhgef7 Rattus norvegicus O55043
Anti Bait CoIP
20080968
Intra Slc9a3 P26433 Shank2 Rattus norvegicus Q9QX74
SPR
16293618
Intra Slc9a3 P26433 Shank2 Rattus norvegicus Q9QX74
Y2H
16293618
Intra Slc9a3 P26433 Chp2 Rattus norvegicus Q810D1
IF
12576672
Intra Slc9a3 P26433 Chp2 Rattus norvegicus Q810D1
Far-WB
12576672
Intra Slc9a3 P26433 Chp2 Rattus norvegicus Q810D1
Pull Down
12576672
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13343 SLC9A3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc9a3 NCBI NCBI:6550
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