2. Gene
  3. Bcar1 - BCAR1 scaffold protein, Cas family member Gene

Bcar1 - BCAR1 scaffold protein, Cas family member Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cas; Crkas; P130CAS

基因 ID: 25414 | 基因类型: protein coding

关于 Bcar1

功能概要

Enables protein domain specific binding activity. Involved in several processes, including cellular response to endothelin; cellular response to nitric oxide; and transmembrane receptor protein tyrosine kinase signaling pathway. Located in focal adhesion and plasma membrane. Human ortholog(s) of this gene implicated in breast ductal carcinoma. Orthologous to human BCAR1 (BCAR1 scaffold protein, Cas family member). [provided by Alliance of Genome Resources, Apr 2022]

Bcar1 基因产物(3)

mRNA Protein Name
NM_001395122.1 NP_001382051.1 breast cancer anti-estrogen resistance protein 1 isoform 1
NM_001395123.1 NP_001382052.1 breast cancer anti-estrogen resistance protein 1 isoform 2
NM_012931.2 NP_037063.2 breast cancer anti-estrogen resistance protein 1 isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
8940134 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
12011056 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin cytoskeleton organization IMP
IMP: 通过突变表型推断
12011056 RGD
involved in cell migration IMP
IMP: 通过突变表型推断
12011056 RGD
involved in cellular response to endothelin IPI
IPI: 通过物理相互作用推断
12719447 RGD
involved in cellular response to nitric oxide IPI
IPI: 通过物理相互作用推断
12714323 RGD
involved in epidermal growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
9325334 RGD
involved in insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
9627109 RGD
involved in negative regulation of substrate adhesion-dependent cell spreading IMP
IMP: 通过突变表型推断
15817476 RGD
involved in neurotrophin TRK receptor signaling pathway IDA
IDA: 通过直接分析推断
8631760 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in focal adhesion IDA
IDA: 通过直接分析推断
8662921 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

breast cancer anti-estrogen resistance protein 1

BCAR1, Cas family scaffold protein

BCAR1, Cas family scaffolding protein

CRK-associated substrate

breast cancer anti-estrogen resistance 1

v-crk-associated tyrosine kinase substrate

Bcar1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Bcar1 Q63767 PTPN1 Homo sapiens P18031
Pull Down
8940134
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01397 BCAR1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bcar1 NCBI NCBI:9564
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