2. Gene
  3. Ccl3 - C-C motif chemokine ligand 3 Gene

Ccl3 - C-C motif chemokine ligand 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Scya3; MIP-1a

基因 ID: 25542 | 基因类型: protein coding

关于 Ccl3

功能概要

Enables chemokine activity. Involved in several processes, including neutrophil chemotaxis; positive regulation of cytosolic calcium ion concentration; and positive regulation of osteoclast differentiation. Predicted to be located in cytosol and extracellular region. Predicted to be active in extracellular space. Biomarker of several diseases, including Chagas disease; anterior uveitis; nephritis (multiple); renal fibrosis; and status epilepticus. Human ortholog(s) of this gene implicated in human immunodeficiency virus infectious disease. Orthologous to several human genes including CCL3 (C-C motif chemokine ligand 3). [provided by Alliance of Genome Resources, Apr 2022]

Ccl3 基因产物(1)

mRNA Protein Name
NM_013025.2 NP_037157.2 C-C motif chemokine 3 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemokine activity IDA
IDA: 通过直接分析推断
10466578 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in leukocyte chemotaxis IDA
IDA: 通过直接分析推断
7722328 RGD
involved in neutrophil chemotaxis IDA
IDA: 通过直接分析推断
7722328 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
10466578 RGD
involved in positive regulation of osteoclast differentiation IDA
IDA: 通过直接分析推断
9920817 RGD
involved in regulation of programmed cell death IMP
IMP: 通过突变表型推断
19497618 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17666800 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-C motif chemokine 3

MIP-1-alpha

Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3)

chemokine (C-C motif) ligand 3

macrophage inflammatory protein 1-alpha

small-inducible cytokine A3

重组 Ccl3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71898 MIP-1 alpha/CCL3 Protein, Rat P50229 (A24-A92) ≥95%

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-B0498 Bindarit Inhibitor 99.53% Phase 3
Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-149202 UT-11 Inhibitor 99.62% 否
HY-147660 IMMH001 Agonist 98.10% 否
HY-RS02100 CCL3L1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-124668 CCR1 antagonist 12 Antagonist / 否
HY-RS02099 CCL3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS02101 CCL3L3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W505771 Seselin Inhibitor 98.48% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccl3 NCBI NCBI:6348
Mus musculus Ccl3 NCBI NCBI:20302
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