LSM4 - LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated Gene

中文名称：LSM4 同系物、U6 小核 RNA 和 mRNA 降解相关

种属: Homo sapiens

同用名: GRP; YER112W

关于 LSM4

功能概要

该基因编码 RNA 结合蛋白 LSm 家族的成员。 LSm 蛋白形成稳定的异聚体，特异性结合 U6 snRNA 的 3'-末端寡核苷酸 (U) 束，并可能通过介导 U4/U6 snRNP 形成在 pre-mRNA 剪接中发挥作用。已经观察到该基因编码多种亚型的可变剪接转录物变体。[RefSeq 提供，2011 年 11 月]

This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]