1. Gene
  2. Ppia - peptidylprolyl isomerase A Gene

Ppia - peptidylprolyl isomerase A Gene

种属: Mus musculus

同用名: Cphn; CypA; SP18; CyP-18

基因 ID: 268373 | 基因类型: protein coding

关于 Ppia

功能概要

Enables Integrin binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in platelet aggregation. Acts upstream of or within neuron differentiation. Located in extracellular space and myelin sheath. Is expressed in several structures, including early conceptus; gonad; hemolymphoid system gland; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to human PPIA (peptidylprolyl isomerase A). [provided by Alliance of Genome Resources, Apr 2022]

Ppia 基因产物(1)

mRNA Protein Name
NM_008907.2 NP_032933.1 peptidyl-prolyl cis-trans isomerase A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables integrin binding IDA
IDA: 通过直接分析推断
24429998 MGI
enables peptidyl-prolyl cis-trans isomerase activity IMP
IMP: 通过突变表型推断
24429998 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16352598 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within neuron differentiation IMP
IMP: 通过突变表型推断
16352598 MGI
involved in platelet activation IMP
IMP: 通过突变表型推断
24429998 MGI
involved in platelet aggregation IMP
IMP: 通过突变表型推断
24429998 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
29921611 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

peptidyl-prolyl cis-trans isomerase A

PPIase A

cyclophilin A

cyclosporin A-binding protein

rotamase A

重组 Ppia 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70007 Cyclophilin A Protein, Mouse (solution) P17742 (M1-L164) ≥95%
HY-P74212 Cyclophilin A Protein, Mouse (His) P17742/NP_032933.1 (M1-L164) ≥95%
HY-P70007A Cyclophilin A Protein, Mouse P17742 (M1-L164) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppia NCBI NCBI:5478