2. Gene
  3. Slamf1 - signaling lymphocytic activation molecule family member 1 Gene

Slamf1 - signaling lymphocytic activation molecule family member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Slam; CD150; IPO-3; CDw150; ESTM51; 4933415F16

基因 ID: 27218 | 基因类型: protein coding

关于 Slamf1

功能概要

Enables identical protein binding activity and signaling receptor activity. Involved in natural killer cell activation; positive regulation of activated T cell proliferation; and regulation of cytokine production. Acts upstream of or within several processes, including leukocyte chemotaxis involved in inflammatory response; positive regulation of leukocyte chemotaxis; and regulation of vesicle fusion. Located in external side of plasma membrane and phagocytic vesicle. Is expressed in liver lobe. Orthologous to human SLAMF1 (signaling lymphocytic activation molecule family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slamf1 基因产物(2)

mRNA Protein Name
NM_001360898.1 NP_001347827.1 signaling lymphocytic activation molecule isoform 2 precursor
NM_013730.4 NP_038758.2 signaling lymphocytic activation molecule isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
25799045 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10970095 MGI
enables signaling receptor activity IDA
IDA: 通过直接分析推断
25799045 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within leukocyte chemotaxis involved in inflammatory response IMP
IMP: 通过突变表型推断
25799045 MGI
involved in natural killer cell differentiation IMP
IMP: 通过突变表型推断
18031695 MGI
involved in natural killer cell proliferation IMP
IMP: 通过突变表型推断
18031695 MGI
involved in negative regulation of T cell cytokine production IDA
IDA: 通过直接分析推断
11477403 MGI
involved in negative regulation of type II interferon production IDA
IDA: 通过直接分析推断
11477403 MGI
involved in positive regulation of T-helper 1 cell cytokine production IDA
IDA: 通过直接分析推断
9126961 MGI
involved in positive regulation of activated T cell proliferation IDA
IDA: 通过直接分析推断
9126961 MGI
acts upstream of or within positive regulation of dendritic cell chemotaxis IMP
IMP: 通过突变表型推断
25799045 MGI
acts upstream of or within positive regulation of macrophage chemotaxis IMP
IMP: 通过突变表型推断
22960654 MGI
involved in positive regulation of type II interferon production IDA
IDA: 通过直接分析推断
9126961 MGI
acts upstream of or within regulation of catalytic activity IMP
IMP: 通过突变表型推断
22493499 MGI
acts upstream of or within regulation of vesicle fusion IMP
IMP: 通过突变表型推断
22493499 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
22960654 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
18971422 MGI
located in phagocytic vesicle IDA
IDA: 通过直接分析推断
22493499 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

signaling lymphocytic activation molecule

SLAM family member 1

signaling lymphocyte activation molecule

Slamf1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Slamf1 Q9QUM4 UVRAG Homo sapiens Q9P2Y5
Anti Bait CoIP
22493499
种属内
Slamf1 Q9QUM4 Fyn Mus musculus P39688
Pull Down
16847311
种属内
Slamf1 Q9QUM4 Fyn Mus musculus P39688
Anti Bait CoIP
16847311
种属内
Slamf1 Q9QUM4 Fyn Mus musculus P39688
Pull Down
11477403
种属内
Slamf1 Q9QUM4 Fyn Mus musculus P39688
Anti Bait CoIP
11477403
种属内
Slamf1 Q9QUM4 Fyn Mus musculus P39688
Pull Down
12545173
种属内
Slamf1 Q9QUM4 Sh2d1a Mus musculus O88890
Pull Down
12545173
种属内
Slamf1 Q9QUM4 Sh2d1a Mus musculus O88890
CoIP
11477403
种属内
Slamf1 Q9QUM4 Sh2d1a Mus musculus O88890
Anti Bait CoIP
16847311
种属间
Slamf1 Q9QUM4 BECN1 Homo sapiens Q14457
Anti Bait CoIP
22493499
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 Slamf1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72467 CD150/SLAMF1 Protein, Mouse (HEK293, His) Q9QUM4-1 (T25-P242) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12979 SLAMF1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slamf1 NCBI NCBI:6504
Rattus norvegicus Slamf1 NCBI NCBI:498286
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