1. Gene
  2. GNG10 - G protein subunit gamma 10 Gene

GNG10 - G protein subunit gamma 10 Gene

中文名称:G 蛋白亚基γ10

种属: Homo sapiens

基因 ID: 2790 | 基因类型: protein coding

关于 GNG10

Cytogenetic location: 9q31.3 Genomic coordinates (GRCh38): 9:111,661,605-111,670,226 (from NCBI)

This gene has 1 transcript (splice variant), 175 orthologues and 11 paralogues. Ubiquitous expression in appendix (RPKM 57.2), adrenal (RPKM 51.1) and 25 other tissues.

功能概要

预测启用 G 蛋白 β-亚基结合活性。预测参与 G 蛋白偶联受体信号通路。预测位于质膜中。预计是异源三聚体 G 蛋白复合物的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. [provided by Alliance of Genome Resources, Apr 2022]

GNG10 基因产物(2)

mRNA Protein Name
NM_001017998.4 NP_001017998.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
NM_001198664.2 NP_001185593.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

GNG10 蛋白结构

G-gamma

G-gamma: GGL domain (9 - 66)

  • 0
  • 68 a.a.
蛋白主名 其他名称

guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10

guanine nucleotide binding protein (G protein), gamma 10

GNG10 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
GNG10 P50151 KRT34 Homo sapiens O76011 32296183
种属内
GNG10 P50151 KRT34 Homo sapiens O76011 32296183
种属内
GNG10 P50151 KRT38 Homo sapiens O76015 31515488
种属内
GNG10 P50151 KRT38 Homo sapiens O76015 25416956
种属内
GNG10 P50151 KRT38 Homo sapiens O76015 25416956
种属内
GNG10 P50151 KRT38 Homo sapiens O76015 29892012
种属内
GNG10 P50151 KRT16 Homo sapiens P08779 32296183
种属内
GNG10 P50151 KRT16 Homo sapiens P08779 32296183
种属内
GNG10 P50151 TCF4 Homo sapiens P15884 25416956
种属内
GNG10 P50151 TCF4 Homo sapiens P15884 25416956
种属内
GNG10 P50151 KRT31 Homo sapiens Q15323 25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Good Syndrome

Immunodeficiency With Thymoma

Thymoma-Immunodeficiency Syndrome

Thymoma With Hypogammaglobulinemia

Thymoma Immunodeficiency

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus GNG10 VGNC VGNC:56971
Canis familiaris GNG10 VGNC VGNC:97200
Rattus norvegicus GNG10 RGD RGD:621514
Mus musculus GNG10 MGD MGI:1336169