2. Gene
  3. GAS2L3 - growth arrest specific 2 like 3 Gene

GAS2L3 - growth arrest specific 2 like 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：生长停滞特异性 2 样 3

种属: Homo sapiens

同用名: G2L3

基因 ID: 283431 | 基因类型: protein coding

关于 GAS2L3

Cytogenetic location: 12q23.1 Genomic coordinates (GRCh38): 12:100,573,684-100,628,288 (from NCBI)

This gene has 9 transcripts (splice variants), 201 orthologues and 36 paralogues. Broad expression in gall bladder (RPKM 2.2), colon (RPKM 1.8) and 23 other tissues.

功能概要

启用肌动蛋白结合活性和微管结合活性。参与肌动蛋白细胞骨架组织和微管细胞骨架组织。位于肌动蛋白细胞骨架和微管细胞骨架中。 [由基因组资源联盟提供，2022 年 4 月]

Enables actin binding activity and microtubule binding activity. Involved in actin Cytoskeleton organization and microtubule Cytoskeleton organization. Located in actin Cytoskeleton and microtubule Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

GAS2L3 基因产物(4)

mRNA Protein Name
NM_001303130.2 NP_001290059.1 GAS2-like protein 3 isoform a
NM_001303131.2 NP_001290060.1 GAS2-like protein 3 isoform b
NM_001363672.2 NP_001350601.1 GAS2-like protein 3 isoform a
NM_174942.3 NP_777602.1 GAS2-like protein 3 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IDA
IDA: 通过直接分析推断
21561867 GOA
enables microtubule binding IDA
IDA: 通过直接分析推断
21561867 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
24571573 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin cytoskeleton organization IDA
IDA: 通过直接分析推断
21561867 GOA
involved in microtubule cytoskeleton organization IDA
IDA: 通过直接分析推断
21561867 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
21561867 GOA
located in microtubule cytoskeleton IDA
IDA: 通过直接分析推断
21561867 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GAS2L3 蛋白结构

CH

CH: Calponin homology (CH) domain (57 - 166)

GAS2

GAS2: Growth-Arrest-Specific Protein 2 Domain (212 - 283)

  • 0
  • 200
  • 400
  • 600
  • 694 a.a.
蛋白主名 其他名称

GAS2-like protein 3

growth arrest-specific protein 2-like 3

GAS2L3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra GAS2L3 Q86XJ1 MYL6 Homo sapiens P60660
Y2H Array
32296183
Intra GAS2L3 Q86XJ1 BIRC5 Homo sapiens O15392
Pull Down
24571573
Intra GAS2L3 Q86XJ1 BIRC5 Homo sapiens O15392
Anti Bait CoIP
24571573
Intra GAS2L3 Q86XJ1 AURKB Homo sapiens Q96GD4
Pull Down
24571573
Intra GAS2L3 Q86XJ1 AURKB Homo sapiens Q96GD4
IF
24571573
Intra GAS2L3 Q86XJ1 AURKB Homo sapiens Q96GD4
Anti Bait CoIP
24571573
Intra GAS2L3 Q86XJ1 TSR2 Homo sapiens Q969E8
Validated Y2H
32296183
Intra GAS2L3 Q86XJ1 CDCA8 Homo sapiens Q53HL2
Pull Down
24571573
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Anemia, Congenital Dyserythropoietic, Type Iiia

Congenital Dyserythropoietic Anemia, Type Iii

Cdan3

Congenital Dyserythropoietic Anemia Type Iii

Cda Iii

Congenital Dyserythropoietic Anemia Type 3

CDAN3A

Dyserythropoietic Anemia, Congenital, Type Iiia

Cda, Type Iiia

Anemia, Congenital Dyserythropoietic, Type Iii

Anemia With Multinucleated Erythroblasts

Cda Type 3

Cda Type Iii

Dyserythropoietic Anemia, Congenital Type 3

Cda, Type Iii

Erythroreticulosis, Hereditary Benign

Anaemia With Multinucleated Erythroblasts

Congenital Dyserythropoietic Anaemia Type 3

Congenital Dyserythropoietic Anaemia Type Iii

Hereditary Benign Erythroreticulosis

Anemia, Congenital Dyserythropoietic, 3a

Anemia With Multinucleated Erythroblasts Erythroreticulosis, Hereditary Benign
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05284 GAS2L3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta GAS2L3 VGNC VGNC:72794
Felis catus GAS2L3 VGNC VGNC:62468
Rattus norvegicus GAS2L3 RGD RGD:1594151
Bos taurus GAS2L3 VGNC VGNC:29260
Mus musculus GAS2L3 MGD MGI:1918780
Canis familiaris GAS2L3 VGNC VGNC:41117
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