LIN9 - lin-9 DREAM MuvB core complex component Gene

中文名称：lin-9 DREAM MuvB 核心复杂组件

种属: Homo sapiens

同用名: TGS; BARA; TGS1; TGS2; Lin-9; BARPsv

关于 LIN9

功能概要

该基因编码一种肿瘤抑制蛋白，该蛋白通过与成视网膜细胞瘤 1 蛋白结合来抑制 DNA 合成和致癌转化。编码的蛋白质还与其他细胞周期调节因子的复合物相互作用，以抑制非分裂细胞中细胞周期依赖性基因的表达。已经观察到该基因编码多种亚型的可变剪接转录物变体。[RefSeq 提供，2012 年 7 月]

This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of Other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]