2. Gene
  3. ASTE1 - asteroid homolog 1 Gene

ASTE1 - asteroid homolog 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：小行星同系物 1

种属: Homo sapiens

同用名: HT001

基因 ID: 28990 | 基因类型: protein coding

关于 ASTE1

This gene has 8 transcripts (splice variants) and 211 orthologues. Ubiquitous expression in testis (RPKM 3.6), thyroid (RPKM 3.3) and 25 other tissues.

功能概要

预测启用核酸酶活性。预测参与核酸磷酸二酯键的水解。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable nuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. [provided by Alliance of Genome Resources, Apr 2022]

ASTE1 基因产物(2)

mRNA Protein Name
NM_001288950.2 NP_001275879.1 protein asteroid homolog 1 isoform 1
NM_014065.4 NP_054784.2 protein asteroid homolog 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3' overhang single-stranded DNA endodeoxyribonuclease activity IDA
IDA: 通过直接分析推断
34354233 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables single-stranded DNA endodeoxyribonuclease activity IDA
IDA: 通过直接分析推断
34354233 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in double-strand break repair via homologous recombination IMP
IMP: 通过突变表型推断
34354233 GOA
involved in double-strand break repair via nonhomologous end joining IMP
IMP: 通过突变表型推断
34354233 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ASTE1 蛋白结构

XPG_N

XPG_N: XPG N-terminal domain (1 - 96)

XPG_I_2

XPG_I_2: XPG domain containing (116 - 236)

  • 0
  • 200
  • 400
  • 600
  • 679 a.a.
蛋白主名 其他名称

protein asteroid homolog 1

ASTE1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ASTE1 Q2TB18 XRCC4 Homo sapiens Q13426
Validated Y2H
25416956
种属内
ASTE1 Q2TB18 XRCC4 Homo sapiens Q13426
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Osgood-Schlatter'S Disease

Osgood-Schlatter Disease

Juvenile Osteochondrosis Of Tibial Tubercle

Osteochondrosis

Osteochondritis Of Tibial Tubercle

Osteochondrosis Of Proximal Tibia

Aseptic Necrosis Of The Tibial Tubercle

Osteochondrosis Of The Tibial Tubercle

Osteochondritis Juvenilis
Lynch Syndrome

Hereditary Nonpolyposis Colon Cancer

Hereditary Nonpolyposis Colorectal Cancer

Hereditary Nonpolyposis Colorectal Carcinoma

Hereditary Nonpolyposis Colorectal Neoplasms

Familial Nonpolyposis Colon Cancer

Hnpcc

Coca 1

Hereditary Defective Mismatch Repair Syndrome

Hereditary Non-Polyposis Colon Cancer

Hereditary Non-Polyposis Colon Cancer Syndrome

Hereditary Non-Polyposis Colorectal Cancer

Hereditary Non-Polyposis Colorectal Cancer Syndrome

Hereditary Nonpolyposis Colon Cancer Syndrome

Hereditary Nonpolyposis Colorectal Cancer Syndrome

Hereditary Nonpolyposis Colorectal Neoplasm

Hnpcc - Hereditary Nonpolyposis Colon Cancer

Cancer Family Syndrome

Familial Nonpolyposis Colorectal Cancer

Colon Cancer, Familial Nonpolyposis

Colorectal Neoplasms, Hereditary Nonpolyposis

Cancer, Colorectal, Nonpolyposis, Hereditary

Colorectal Cancer, Hereditary Nonpolyposis, Type 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01110 ASTE1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ASTE1 RGD RGD:1304643
Canis familiaris ASTE1 VGNC VGNC:52864
Felis catus ASTE1 VGNC VGNC:59981
Mus musculus ASTE1 MGD MGI:1913845
Bos taurus ASTE1 VGNC VGNC:26225
Macaca mulatta ASTE1 VGNC VGNC:84874
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