1. Gene
  2. Btg2 - BTG anti-proliferation factor 2 Gene

Btg2 - BTG anti-proliferation factor 2 Gene

种属: Rattus norvegicus

同用名: An; Agl; Pc3; an-1; Tis21

基因 ID: 29619 | 基因类型: protein coding

关于 Btg2

功能概要

Enables transcription corepressor activity. Involved in several processes, including negative regulation of neuron apoptotic process; response to electrical stimulus; and response to peptide hormone. Acts upstream of or within negative regulation of apoptotic process; negative regulation of transcription by RNA polymerase II; and neuron differentiation. Predicted to be active in cytoplasm and nucleus. Biomarker of acute necrotizing pancreatitis and brain ischemia. Orthologous to human BTG2 (BTG anti-proliferation factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Btg2 基因产物(1)

mRNA Protein Name
NM_017259.2 NP_058955.1 protein BTG2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11237868 RGD
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
20020054 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to phorbol 13-acetate 12-myristate IEP
IEP: 通过表达模式推断
2005087 RGD
acts upstream of or within negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
12360398 RGD
involved in negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
12360398 RGD
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
20020054 RGD
acts upstream of or within neuron differentiation IDA
IDA: 通过直接分析推断
12360398 RGD
involved in neuron differentiation IEP
IEP: 通过表达模式推断
23000394 RGD
involved in response to electrical stimulus IEP
IEP: 通过表达模式推断
8879470 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
15519684 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
8263025 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein BTG2

B-cell translocation gene 2, anti-proliferative

BTG family, member 2

Early induced gene B-cell translocation gene 2

NGF-inducible anti-proliferative protein PC3

NGF-inducible anti-proliferative putative secreted protein

cell surface alloantigen

Btg2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra Btg2 P27049 Pick1 Rattus norvegicus Q9EP80
Pull Down
11237868
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Btg2 NCBI NCBI:7832