2. Gene
  3. NCAPH2 - non-SMC condensin II complex subunit H2 Gene

NCAPH2 - non-SMC condensin II complex subunit H2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：非 SMC 凝聚素 II 复合亚基 H2

种属: Homo sapiens

同用名: CAPH2

基因 ID: 29781 | 基因类型: protein coding

关于 NCAPH2

Cytogenetic location: 22q13.33 Genomic coordinates (GRCh38): 22:50,508,224-50,524,780 (from NCBI)

This gene has 10 transcripts (splice variants) and 191 orthologues. Ubiquitous expression in bone marrow (RPKM 17.2), testis (RPKM 13.4) and 25 other tissues.

功能概要

该基因编码凝缩蛋白 II 复合物的非 SMC 亚基之一。该复合物在有丝分裂染色体组装中起着至关重要的作用。该基因的交替剪接导致多个转录变体。[RefSeq 提供，2010 年 5 月]

This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010]

NCAPH2 基因产物(3)

mRNA Protein Name
NM_001185011.2 NP_001171940.1 condensin-2 complex subunit H2 isoform 3
NM_014551.5 NP_055366.3 condensin-2 complex subunit H2 isoform 1
NM_152299.4 NP_689512.2 condensin-2 complex subunit H2 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17268547 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NCAPH2 蛋白结构

CNDH2_N

CNDH2_N: Condensin II complex subunit CAP-H2 or CNDH2, N-terminal (51 - 605)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 605 a.a.
蛋白主名 其他名称

condensin-2 complex subunit H2

CAP-H2 subunit of the condensin II complex

NCAPH2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra NCAPH2 Q6IBW4 NCAPG2 Homo sapiens Q86XI2
Anti Tag CoIP
33961781
Intra NCAPH2 Q6IBW4 NCAPG2 Homo sapiens Q86XI2
Pull Down
17268547
Intra NCAPH2 Q6IBW4 NCAPG2 Homo sapiens Q86XI2
Anti Bait CoIP
17268547
Intra NCAPH2 Q6IBW4 SMC2 Homo sapiens O95347
Anti Tag CoIP
33961781
Intra NCAPH2 Q6IBW4 SMC2 Homo sapiens O95347
Anti Bait CoIP
17268547
Intra NCAPH2 Q6IBW4 SMC2 Homo sapiens O95347
Anti Tag CoIP
35271311
Intra NCAPH2 Q6IBW4 SMC2 Homo sapiens O95347
Pull Down
17268547
Intra NCAPH2 Q6IBW4 SMC4 Homo sapiens Q9NTJ3
Pull Down
17268547
Intra NCAPH2 Q6IBW4 SMC4 Homo sapiens Q9NTJ3
Anti Tag CoIP
33961781
Intra NCAPH2 Q6IBW4 NCAPD3 Homo sapiens P42695
Pull Down
17268547
Intra NCAPH2 Q6IBW4 NCAPD3 Homo sapiens P42695
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Myopia 6

MYP6

Myopia, Susceptibility To

Myopia, Type 6
Fatal Infantile Cardioencephalomyopathy Due To Cytochrome C Oxidase Deficiency

Cardioencephalomyopathy, Fatal Infantile, Due To Cytochrome C Oxidase Deficiency

Fatal Infantile Cox Deficiency

Fatal Infantile Cytochrome C Oxidase Deficiency

Fatal Infantile Encephalocardiomyopathy
Mitochondrial Complex Iv Deficiency, Nuclear Type 2

Cardioencephalomyopathy, Fatal Infantile, Due To Cytochrome C Oxidase Deficiency 1

MC4DN2

Cemcox1

Mitochondrial Complex Ii Deficiency, Nuclear Type 4

MC2DN4

Mitochondrial Complex 2 Deficiency, Nuclear Type 4

Cytochrome C Oxidase Deficiency, Fatal Infantile, With Cardioencephalomyopathy

Fatal Infantile Cardioencephalomyopathy Due To Cytochrome C Oxidase Deficiency 1

Cytochrome C Oxidase Deficiency With Fatal Infantile Cardioencephalomyopathy

Cardioencephalomyopathy, Fatal Infantile, Due To Cytochrome C Oxidase Deficiency
Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy

Primary Dilated Cardiomyopathy

Idiopathic Dilated Cardiomyopathy

Congestive Cardiomyopathy

Idiopathic Dilation Cardiomyopathy

Primary Familial Dilated Cardiomyopathy

Cardiomyopathy, Dilated

DCM

Cardiomyopathy, Familial Dilated

Dilated Cardiomyopathy, Familial

Hypokinetic Dilated Cardiomyopathy, Familial

Familial Idiopathic Cardiomyopathy

Fdc

Cardiomyopathy, Familial Idiopathic

Idiopathic Cardiomegaly

Dilated Congestive Cardiomyopathy

Chronic Dilated Cardiomyopathy

Ccm - [Congestive Cardiomyopathy]

Cocm - [Congestive Cardiomyopathy]

Dcm - [Dilated Cardiomyopathy]

Dilated-Hypokinetic Cardiomyopathy

Congestive Idiopathic Cardiomyopathy

Primary Idiopathic Dilated Cardiomyopathy
Pleural Empyema

Empyema

Pyothorax

Empyema, Pleural

Abscess Of Pleural Cavity

Abscess Of Thorax

Empyema Of Pleura

Empyema Of Pleura Without Fistula

Empyema With Fistula

Empyema With No Fistula

Empyema With Pleural Fistula

Empyema Without Mention Of Fistula

Empyema, Chest

Lung Empyema

Pleural Empyema With Fistula

Pleural Empyema With No Fistula

Purulent Pleurisy

Purulent Pleuritis

Thorax Abscess

Pyopneumothorax
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09071 NCAPH2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris NCAPH2 VGNC VGNC:43644
Rattus norvegicus NCAPH2 RGD RGD:1565937
Macaca mulatta NCAPH2 VGNC VGNC:75018
Felis catus NCAPH2 VGNC VGNC:63735
Bos taurus NCAPH2 VGNC VGNC:31906
Mus musculus NCAPH2 MGD MGI:1289164
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