1. Gene
  2. Gpr119 - G protein-coupled receptor 119 Gene

Gpr119 - G protein-coupled receptor 119 Gene

中文名称:G 蛋白偶联受体 119

种属: Rattus norvegicus

基因 ID: 302813 | 基因类型: protein coding

关于 Gpr119

Primary_assembly X: 127,852,145-127,858,198 reverse strand.mRatBN7.2:CM026994.1

This gene has 1 transcript (splice variant), 176 orthologues, 18 paralogues and is associated with 2 phenotypes. Biased expression in Brain (RPKM 6.3), Spleen (RPKM 1.1) and 8 other tissues.

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联受体活性和磷脂酰胆碱结合活性。预计参与腺苷酸环化酶激活 G 蛋白偶联受体信号通路和代谢过程的调控。预计作用于胰岛素分泌的上游或内部。预计是膜的组成部分。预计是受体复合体的一部分。预计在细胞质和质膜中有活性。与人类 GPR119(G 蛋白偶联受体 119)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G protein-coupled receptor activity and phosphatidylcholine binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within Insulin secretion. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human GPR119 (G protein-coupled receptor 119). [provided by Alliance of Genome Resources, Apr 2022]

Gpr119 基因产物(1)

mRNA Protein Name
NM_181770.1 NP_861435.1 glucose-dependent insulinotropic receptor

Gpr119 蛋白结构

7tmA_GPR119_R_insulinotropic_receptor

7tmA_GPR119_R_insulinotropic_receptor: cd15104 (5 - 289)

7tmA_GPR119_R_insulinotropic_receptor

7tmA_GPR119_R_insulinotropic_receptor: cd15104 (6 - 31)

7tmA_GPR119_R_insulinotropic_receptor

7tmA_GPR119_R_insulinotropic_receptor: cd15104 (39 - 65)

7tmA_GPR119_R_insulinotropic_receptor

7tmA_GPR119_R_insulinotropic_receptor: cd15104 (77 - 107)

7tmA_GPR119_R_insulinotropic_receptor

7tmA_GPR119_R_insulinotropic_receptor: cd15104 (119 - 139)

7tmA_GPR119_R_insulinotropic_receptor

7tmA_GPR119_R_insulinotropic_receptor: cd15104 (161 - 190)

7tmA_GPR119_R_insulinotropic_receptor

7tmA_GPR119_R_insulinotropic_receptor: cd15104 (217 - 247)

7tmA_GPR119_R_insulinotropic_receptor

7tmA_GPR119_R_insulinotropic_receptor: cd15104 (257 - 282)

KLF18_N

KLF18_N: cl40479 (345 - 452)

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  • 468 a.a.
蛋白主名 其他名称

glucose-dependent insulinotropic receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gpr119 NCBI NCBI:139760