Sirt7 - sirtuin 7 Gene

中文名称：沉默信息调节因子 2 相关酶类 7

种属: Rattus norvegicus

关于 Sirt7

功能概要

预计该基因编码的蛋白在线性酰胺中实现多种功能，包括水解酶活性，作用于碳-氮（但不是肽）键；蛋白质-丙酰赖氨酸脱丙酰酶活性；和转录辅阻遏物活性。预计参与多个过程，包括细胞大分子生物合成过程；蛋白质脱酰；和调节含核碱基的化合物代谢过程。预测位于核斑点；核仁组织区；和双链断裂位点。预计活跃于核心。与人类 SIRT7（sirtuin 7）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; protein-propionyllysine depropionylase activity; and transcription corepressor activity. Predicted to be involved in several processes, including cellular macromolecule biosynthetic process; protein deacylation; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in nuclear speck; nucleolus organizer region; and site of double-strand break. Predicted to be active in nucleus. Orthologous to human SIRT7 (Sirtuin 7). [provided by Alliance of Genome Resources, Apr 2022]