1. Gene
  2. Cd3e - CD3 epsilon subunit of T-cell receptor complex Gene

Cd3e - CD3 epsilon subunit of T-cell receptor complex Gene

种属: Rattus norvegicus

基因 ID: 315609 | 基因类型: protein coding

关于 Cd3e

功能概要

Predicted to enable several functions, including SH3 domain binding activity; identical protein binding activity; and protein heterodimerization activity. Involved in T cell differentiation in thymus; positive regulation of T cell proliferation; and response to nutrient. Predicted to be located in several cellular components, including cell body; dendritic spine; and immunological synapse. Predicted to be part of alpha-beta T cell receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 18. Orthologous to human CD3e (CD3e molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd3e 基因产物(1)

mRNA Protein Name
NM_001108140.2 NP_001101610.2 T-cell surface glycoprotein CD3 epsilon chain precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell differentiation in thymus IEP
IEP: 通过表达模式推断
11896936 RGD
involved in positive regulation of T cell proliferation IDA
IDA: 通过直接分析推断
10498748 RGD
involved in response to nutrient IDA
IDA: 通过直接分析推断
10498748 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

T-cell surface glycoprotein CD3 epsilon chain

CD3 antigen, epsilon polypeptide

CD3 molecule, epsilon polypeptide

CD3e molecule

重组 Cd3e 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76788 CD3 epsilon Protein, Rat (HEK293, Fc) NP_001101610.1 (Y24-D103) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd3e NCBI NCBI:916
Canis familiaris Cd3e NCBI NCBI:442981
Macaca fascicularis Cd3e NCBI NCBI:102133065
Mus musculus Cd3e NCBI NCBI:12501
Macaca mulatta Cd3e NCBI NCBI:699467