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RAB37 - RAB37, member RAS oncogene family Gene

中文名称:RAB37,RAS 致癌基因家族成员

种属: Homo sapiens

基因 ID: 326624 | 基因类型: protein coding

关于 RAB37

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,671,131-74,747,335 (from NCBI)

This gene has 16 transcripts (splice variants), 168 orthologues and 68 paralogues. Broad expression in spleen (RPKM 9.4), bone marrow (RPKM 7.1) and 20 other tissues.

功能概要

Rab 蛋白是低分子量 GTP 酶,是囊泡运输的关键调节剂。有关 Rab 蛋白的其他背景信息,请参阅 MIM 179508。[OMIM 提供,2006 年 4 月]

Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking. For additional background information on Rab proteins, see MIM 179508.[supplied by OMIM, Apr 2006]

RAB37 基因产物(5)

mRNA Protein Name
NM_001006638.3 NP_001006639.1 ras-related protein Rab-37 isoform 2
NM_001163989.3 NP_001157461.2 ras-related protein Rab-37 isoform 4
NM_001163990.2 NP_001157462.1 ras-related protein Rab-37 isoform 5
NM_001330471.2 NP_001317400.1 ras-related protein Rab-37 isoform 6
NM_175738.5 NP_783865.1 ras-related protein Rab-37 isoform 3
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: 通过直接分析推断
15308636 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RAB37 蛋白结构

Ras

Ras: Ras family (31 - 191)

  • 0
  • 100
  • 200
  • 223 a.a.
蛋白主名 其他名称

ras-related protein Rab-37

RAB37, member of RAS oncogene family

RAB37 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra RAB37 Q96AX2 MAL2 Homo sapiens Q969L2
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Prostate Transitional Cell Carcinoma

Transitional Cell Carcinoma Of Prostate

Primary Prostate Urothelial Carcinoma

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus RAB37 MGD MGI:1929945
Rattus norvegicus RAB37 RGD RGD:2319982
Canis familiaris RAB37 VGNC VGNC:45279
Macaca mulatta RAB37 VGNC VGNC:81535
Bos taurus RAB37 VGNC VGNC:33645
Felis catus RAB37 VGNC VGNC:97589