2. Gene
  3. Frs2 - fibroblast growth factor receptor substrate 2 Gene

Frs2 - fibroblast growth factor receptor substrate 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: SNT1; SNT-1; Frs2alpha; FRS2-alpha; C330018A15Rik

基因 ID: 327826 | 基因类型: protein coding

关于 Frs2

功能概要

Enables transmembrane receptor protein tyrosine kinase adaptor activity. Acts upstream of or within several processes, including animal organ development; organ induction; and regulation of MAPK cascade. Located in cell-cell junction; cytoplasm; and plasma membrane. Is expressed in several structures, including alimentary system; blastocyst; central nervous system; genitourinary system; and immune system. Orthologous to human FRS2 (Fibroblast Growth Factor receptor substrate 2). [provided by Alliance of Genome Resources, Apr 2022]

Frs2 基因产物(24)

mRNA Protein Name
NM_001408282.1 NP_001395211.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408283.1 NP_001395212.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408284.1 NP_001395213.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408285.1 NP_001395214.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408286.1 NP_001395215.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408287.1 NP_001395216.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408288.1 NP_001395217.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408289.1 NP_001395218.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408290.1 NP_001395219.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408291.1 NP_001395220.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408292.1 NP_001395221.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408293.1 NP_001395222.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408294.1 NP_001395223.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408295.1 NP_001395224.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408296.1 NP_001395225.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408297.1 NP_001395226.1 fibroblast growth factor receptor substrate 2 isoform 1
NM_001408308.1 NP_001395237.1 fibroblast growth factor receptor substrate 2 isoform 2
NM_001408309.1 NP_001395238.1 fibroblast growth factor receptor substrate 2 isoform 2
NM_001408310.1 NP_001395239.1 fibroblast growth factor receptor substrate 2 isoform 2
NM_001408311.1 NP_001395240.1 fibroblast growth factor receptor substrate 2 isoform 2
NM_001408312.1 NP_001395241.1 fibroblast growth factor receptor substrate 2 isoform 2
NM_001408313.1 NP_001395242.1 fibroblast growth factor receptor substrate 2 isoform 2
NM_001408314.1 NP_001395243.1 fibroblast growth factor receptor substrate 2 isoform 2
NM_177798.4 NP_808466.1 fibroblast growth factor receptor substrate 2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9182757 MGI
enables transmembrane receptor protein tyrosine kinase adaptor activity IDA
IDA: 通过直接分析推断
9182757 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within anterior/posterior axis specification, embryo IMP
IMP: 通过突变表型推断
15870281 MGI
acts upstream of or within cell surface receptor protein tyrosine kinase signaling pathway IDA
IDA: 通过直接分析推断
9182757 MGI
acts upstream of or within fibroblast growth factor receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
11585837 MGI
acts upstream of or within fibroblast growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
23136392 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
16239343 MGI
acts upstream of or within gastrulation with mouth forming second IMP
IMP: 通过突变表型推断
15870281 MGI
acts upstream of or within lens development in camera-type eye IMP
IMP: 通过突变表型推断
23136392 MGI
acts upstream of or within lens fiber cell development IGI
IGI: 通过遗传相互作用推断
23136392 MGI
acts upstream of or within lens fiber cell development IMP
IMP: 通过突变表型推断
23136392 MGI
acts upstream of or within lens placode formation involved in camera-type eye formation IMP
IMP: 通过突变表型推断
15569927 MGI
acts upstream of or within neuroblast proliferation IGI
IGI: 通过遗传相互作用推断
16239343 MGI
acts upstream of or within neuroblast proliferation IMP
IMP: 通过突变表型推断
16239343 MGI
acts upstream of or within organ induction IMP
IMP: 通过突变表型推断
15569927 MGI
acts upstream of or within positive regulation of MAPK cascade IMP
IMP: 通过突变表型推断
15569927 MGI
acts upstream of or within prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis IMP
IMP: 通过突变表型推断
18184727 MGI
acts upstream of or within regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
23782834 MGI
acts upstream of or within regulation of apoptotic process IMP
IMP: 通过突变表型推断
23782834 MGI
acts upstream of or within regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
18184727 MGI
acts upstream of or within ventricular septum development IMP
IMP: 通过突变表型推断
17868091 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
23782834 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
9182757 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
9182757 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fibroblast growth factor receptor substrate 2

FGFR substrate 2

FGFR-signaling adaptor SNT

suc1-associated neurotrophic factor target 1

Frs2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Frs2 Q8C180 Grb2 Mus musculus Q60631
Pull Down
9182757
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-158248 FGFR4-IN-19 Inhibitor / 否
HY-RS05112 FRS2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Frs2 NCBI NCBI:10818
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