1. Gene
  2. HSPA5 - heat shock protein family A (Hsp70) member 5 Gene

HSPA5 - heat shock protein family A (Hsp70) member 5 Gene

中文名称:热休克蛋白家族 A (Hsp70) 成员 5

种属: Homo sapiens

同用名: BIP; GRP78; HEL-S-89n

基因 ID: 3309 | 基因类型: protein coding

关于 HSPA5

Cytogenetic location: 9q33.3 Genomic coordinates (GRCh38): 9:125,234,853-125,241,343 (from NCBI)

This gene has 15 transcripts (splice variants), 248 orthologues and 13 paralogues. Broad expression in thyroid (RPKM 442.6), bone marrow (RPKM 284.6) and 24 other tissues.

功能概要

该基因编码的蛋白质是热休克蛋白 70 (HSP70) 家族的成员。这种蛋白质定位于内质网 (ER) 的腔,在那里它作为典型的 HSP70 伴侣蛋白参与 ER 中蛋白质的折叠和组装,并且是 ER 稳态的主要调节剂。在细胞应激期间,如病毒感染或肿瘤发生期间,该蛋白与跨膜应激传感器蛋白 PERK (蛋白激酶 R 样内质网激酶) 、IRE1 (需要肌醇的激酶 1) 和 ATF6 (激活转录因子 6) 相互作用,其中它充当未折叠蛋白反应 (UPR) 的阻遏物,还在细胞凋亡和衰老中发挥作用。在病毒感染和某些类型的癌细胞中已经报道了这种蛋白质的表达升高和非典型易位到细胞表面。在细胞表面,这种蛋白质可以促进病毒附着和进入宿主细胞。该基因是治疗冠状病毒疾病和化疗耐药癌症的治疗靶点。[RefSeq 提供,2020 年 7 月]

The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. This protein localizes to the lumen of the endoplasmic reticulum (ER) where it operates as a typical HSP70 chaperone involved in the folding and assembly of proteins in the ER and is a master regulator of ER homeostasis. During cellular stress, as during viral Infection or tumorogenesis, this protein interacts with the transmembrane stress sensor proteins PERK (protein kinase R-like endoplasmic reticulum kinase), IRE1 (inositol-requiring kinase 1), and ATF6 (activating transcription factor 6) where it acts as a repressor of the unfolded protein response (UPR) and also plays a role in cellular Apoptosis and senescence. Elevated expression and atypical translocation of this protein to the cell surface has been reported in viral infections and some types of Cancer cells. At the cell surface this protein may facilitate viral attachment and entry to host cells. This gene is a therapeutic target for the treatment of coronavirus diseases and chemoresistant cancers. [provided by RefSeq, Jul 2020]

HSPA5 基因产物(1)

mRNA Protein Name
NM_005347.5 NP_005338.1 endoplasmic reticulum chaperone BiP precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
26655470 GOA
enables ATP hydrolysis activity IDA
IDA: 通过直接分析推断
20335166 GOA
enables enzyme binding IPI
IPI: 通过物理相互作用推断
23921388 GOA
enables misfolded protein binding IDA
IDA: 通过直接分析推断
18400946 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
11907036 GOA
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
12411443 GOA
enables ubiquitin protein ligase binding IPI
IPI: 通过物理相互作用推断
8666824 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucose starvation IDA
IDA: 通过直接分析推断
10085239 GOA
involved in maintenance of protein localization in endoplasmic reticulum IMP
IMP: 通过突变表型推断
23990668 GOA
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
10760948 GOA
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
23990668 GOA
involved in post-translational protein targeting to membrane, translocation IMP
IMP: 通过突变表型推断
29719251 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of COP9 signalosome IDA
IDA: 通过直接分析推断
18850735 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
22689054 GOA
located in cytosol IDA
IDA: 通过直接分析推断
22689054 GOA
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
16223484 GOA
located in endoplasmic reticulum IMP
IMP: 通过突变表型推断
11943137 GOA
part of endoplasmic reticulum chaperone complex IDA
IDA: 通过直接分析推断
18400946 GOA
located in endoplasmic reticulum lumen IDA
IDA: 通过直接分析推断
21289099 GOA
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
11181571 GOA
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: 通过直接分析推断
15308636 GOA
located in intracellular membrane-bounded organelle IDA
IDA: 通过直接分析推断
22689054 GOA
located in midbody IDA
IDA: 通过直接分析推断
15166316 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
22689054 GOA
located in nucleus IMP
IMP: 通过突变表型推断
11943137 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
23349634 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

HSPA5 蛋白结构

HSP70

HSP70: Hsp70 protein (30 - 635)

  • 0
  • 200
  • 400
  • 600
  • 654 a.a.
蛋白主名 其他名称

endoplasmic reticulum chaperone BiP

78 kDa glucose-regulated protein

HSP70 family protein 5

binding-immunoglobulin protein

endoplasmic reticulum lumenal Ca(2+)-binding protein grp78

epididymis secretory sperm binding protein Li 89n

glucose-regulated protein, 78kDa

heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

heat shock protein 70 family protein 5

heat shock protein family A member 5

immunoglobulin heavy chain-binding protein

HSPA5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
HSPA5 P11021 PDIA6 Homo sapiens Q15084
TAP
24189400
种属内
HSPA5 P11021 HYOU1 Homo sapiens Q9Y4L1
Crosslink
30021884
种属内
HSPA5 P11021 HYOU1 Homo sapiens Q9Y4L1
Anti Tag CoIP
26496610
种属内
HSPA5 P11021 UGGT2 Homo sapiens Q9NYU1
Anti Tag CoIP
33961781
种属间
HSPA5 P11021 S Human betacoronavirus K0BRG7
Anti Bait CoIP
29887526
种属间
HSPA5 P11021 S SARS-CoV-2 P0DTC2
Anti Tag CoIP
33965375
种属间
HSPA5 P11021 S SARS-CoV-2 P0DTC2
Confocal
33965375
种属间
HSPA5 P11021 S SARS-CoV-2 P0DTC2
PLA
33965375
种属内
HSPA5 P11021 SIL1 Homo sapiens Q9H173
Anti Tag CoIP
24473200
种属内
HSPA5 P11021 SEC61A1 Homo sapiens P61619
Peptide Array
22796945
种属内
HSPA5 P11021 SEC61A1 Homo sapiens P61619
SPR
22796945
种属内
HSPA5 P11021 HSP90B1 Homo sapiens P14625
Anti Tag CoIP
26496610
种属内
HSPA5 P11021 RAF1 Homo sapiens P04049
Pull Down
18064632
种属内
HSPA5 P11021 RAF1 Homo sapiens P04049
Anti Bait CoIP
18064632
种属内
HSPA5 P11021 RAF1 Homo sapiens P04049
Cosedimentation
18064632
种属内
HSPA5 P11021 PAWR Homo sapiens Q96IZ0
Anti Tag CoIP
19632185
种属内
HSPA5 P11021 PAWR Homo sapiens Q96IZ0
Anti Bait CoIP
19632185
种属内
HSPA5 P11021 PAWR Homo sapiens Q96IZ0
Confocal
19632185
种属内
HSPA5 P11021 DNAJB11 Homo sapiens Q9UBS4
Pull Down
18923428
种属内
HSPA5 P11021 DNAJB11 Homo sapiens Q9UBS4
TAP
24189400
种属内
HSPA5 P11021 ACE2 Homo sapiens Q9BYF1
Pull Down
33965375
种属内
HSPA5 P11021 ACE2 Homo sapiens Q9BYF1
PLA
33965375
种属内
HSPA5 P11021 ACE2 Homo sapiens Q9BYF1
Confocal
33965375
种属内
HSPA5 P11021 ACE2 Homo sapiens Q9BYF1
Anti Tag CoIP
33965375
种属内
HSPA5 P11021 DMKN Homo sapiens Q6E0U4
Anti Bait CoIP
22735594
种属间
HSPA5 P11021 Cnpy2 Mus musculus Q9QXT0
Anti Tag CoIP
28869608
种属内
HSPA5 P11021 ATF6 Homo sapiens P18850
Anti Bait CoIP
27238082
种属间
HSPA5 P11021 Pawr Rattus norvegicus Q62627
Pull Down
19632185
种属间
HSPA5 P11021 Pawr Rattus norvegicus Q62627
Anti Tag CoIP
19632185
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 HSPA5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72239 HSPA5/GRP-78 Protein, Human (His) P11021 (E25-E293) ≥95%

关联疾病

疾病名称 别名
Borna Disease

Enzootic Encephalomyelitis

Peripheral Nervous System Disease

Peripheral Neuropathy

Peripheral Nerve Disease

Peripheral Nerve Disorders

Neuropathy, Peripheral

Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation

Osteoporosis

Postmenopausal Osteoporosis

Osteoporosis, Postmenopausal

Bone Mineral Density Quantitative Trait Locus

Bmnd

Osteoporosis, Involutional

Osteoporosis, Susceptibility To

Osteoporosis, Postmenopausal, Susceptibility

Bone Mineral Density Variation Qtl, Osteoporosis

OSTEOP

Involutional Osteoporosis

Senile Osteoporosis

Osteoporosis Postmenopausal

Bone Mineral Density, Quantitative Trait Locus

Osteoporosis, Senile

Idiopathic Osteoporosis

Bone Rarefaction Nos

Type 1 Osteoporosis

Acute Orbital Inflammation

Acute Inflammation Of Orbit

Cavernous Sinus Thrombosis

Thrombosis Of Cavernous Venous Sinus

Orbital Cellulitis

Cellulitis Of Orbit

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Mucormycosis

Zygomycosis

Disseminated Mucormycosis

Absidia Infection

Absidia Mucoromycosis

Cunninghamella Infection

Cunninghamella Mucoromycosis

Infection By Absidia Spp

Infection By Rhizopus Spp

Mucor Infection

Mucor Mucoromycosis

Infection By Mucor Spp

Rhizopus Infection

Rhizopus Mucoromycosis

Infection By Cunninghamella Spp

Phycomycosis Nos

Epiphyseal Dysplasia, Multiple, With Early-Onset Diabetes Mellitus

Wolcott-Rallison Syndrome

Med-Iddm Syndrome

Iddm-Med Syndrome

Wolcott Rallison Syndrome

WRS

Epiphyseal Dysplasia Multiple With Early-Onset Diabetes Mellitus

Early-Onset Diabetes Mellitus With Multiple Epiphyseal Dysplasia

Multiple Epiphyseal Dysplasia With Early-Onset Diabetes Mellitus

Diabetes Mellitus

Diabetes

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Encephalitis

Mumps Encephalitis

Mumps Meningoencephalitis

Herpes Simplex Neuroinvasion

Herpetic Encephalitis

Herpetic Encephalopathy

Herpes Simplex Encephalitis, Myelitis Or Encephalomyelitis

Encephalitis Due To Herpesviridae

Encephalitis Due To Herpesvirus

Herpes Encephalitis

Herpesviral Encephalitis

Herpes Simplex Encephalitis

Hsv - [Herpes Simplex Virus] Encephalitis

Herpes Virus Encephalitis

Simian B Disease

Simian B Disorder

Encephalitis Nec

Idiopathic Encephalitis

Prion Disease

Spongiform Encephalopathy

Transmissible Spongiform Encephalopathies

Prion Diseases

Prion Disease Pathway

Transmissible Spongiform Encephalopathy

Prion Induced Disorder

Prion Protein Disease

Inherited Human Transmissible Spongiform Encephalopathies

Prion Protein Diseases

Prion-Associated Disorders

Prion-Induced Disorders

Transmissible Dementias

Tses

Human Prion Disease

Tse

Encephalopathy, Transmissible Spongiform

Prion Disease, Susceptibility To

Spongiform Encephalopathies

Human Transmissible Spongiform Encephalopathies, Inherited

Middle East Respiratory Syndrome

Mers

Mers - [Middle East Respiratory Syndrome]

Rheumatoid Arthritis

RA

Arthritis, Rheumatoid

Rheumatoid Arthritis, Susceptibility To

Arthritis Or Polyarthritis, Rheumatic

Atrophic Arthritis

Rheumatism Arthritis

Rheumatoid Polyarthritis

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Dengue Virus

Dengue Virus, Susceptibility To

Dengue Fever, Protection Against

Dengue Fever

Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour

Japanese Encephalitis

Japanese B Encephalitis

Je

Encephalitis Japanese

Encephalitis, Japanese

Russian Autumnal Encephalitis

Je - [Japanese Encephalitis]

Japanese Encephalitis Virus Disease

Jbe - [Japanese B Encephalitis}

B Type Encephalitis

Arthritis

Inflammatory Joint Disease

Inflammatory Disorder Of Joint

Intracranial Sinus Thrombosis

Sinus Thrombosis, Intracranial

Microcephaly 7, Primary, Autosomal Recessive

MCPH7

Primary Autosomal Recessive Microcephaly 7

Microcephaly, Primary Autosomal Recessive, 7

Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma

Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers

Wolfram Syndrome

Didmoad Syndrome

Didmoad

Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness

Wfs

Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, And Deafness

Didmoadud

Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Deafness Syndrome

Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Hearing Loss Syndrome

Ischemia

Acute Coronary Syndrome

Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Cancer Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary

Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis

Conidiobolomycosis

Infection By Conidiobolus

Rhinoentomophthoromycosis

Entomophthoromycosis Conidiobolae

Halothane Hepatitis

Hepatitis Halothane

Autoimmune Cardiomyopathy
Congenital Hypothyroidism

Cretinism

Neonatal Hypothyroidism

Ch

Cht

Congenital Myxedema

Myxedema, Congenital

Endemic Cretinism

Congenital Iodine-Deficiency Syndrome

Fetal Iodine Deficiency Syndrome

Congenital Iodine-Deficiency Hypothyroidism Nos

Myeloma, Multiple

Multiple Myeloma

Kahler Disease

Myelomatosis

Plasma Cell Myeloma

Medullary Plasmacytoma

Multiple Myeloma, Resistance To

Myeloma

Plasma Cell Dyscrasia

Multiple Myeloma, Susceptibility To

Myeloma - Multiple

Kahler'S Disease

Kahler-Bozzolo Disease

Plasma Cell Myelomas

MM

Plasma Cell Neoplasm

Primary Systemic Amyloidosis

Primary Amyloidosis

Immunoglobulin Deposition Disease

Plasmacytic Myeloma

Multiple Myelomata

Multiple Myeloma Nos

Multiple Myeloma Without Mention Of Remission

Monostotic Plasma Cell Myeloma

Mm - [Multiple Myeloma]

Type 2 Diabetes Mellitus

Insulin Resistance

NIDDM

Diabetes Mellitus, Non-Insulin-Dependent

Type 2 Diabetes

T2D

Noninsulin-Dependent Diabetes Mellitus

Diabetes Mellitus, Type Ii

Maturity-Onset Diabetes

Insulin Resistance, Severe, Digenic

Diabetes Mellitus, Type 2

Diabetes Mellitus, Noninsulin-Dependent

Diabetes Mellitus, Noninsulin-Dependent, Association With

Diabetes Mellitus, Noninsulin-Dependent, Late Onset

Hypertension, Insulin Resistance-Related, Susceptibility To

Insulin Resistance, Susceptibility To

Non-Insulin-Dependent Diabetes Mellitus

Type Ii Diabetes Mellitus

Adult-Onset Diabetes Mellitus

Maturity-Onset Diabetes Mellitus

Diabetes Mellitus Type 2

Type Ii Diabetes

Type 2 Diabetes Mellitus, Susceptibility To

Diabetes, Type 2

Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

Diabetes Mellitus, Type 2, Susceptibility To

Diabetes Mellitus, Noninsulin-Dependent, 2

Diabetes Mellitus, Type Ii, Susceptibility To

Hypertension, Insulin Resistance-Related

Adult-Onset Diabetes

Aodm

Diabetes Mellitus, Adult-Onset

Diabetes Mellitus Type Ii

Diabetes Mellitus Type 2, Susceptibility To

Diabetes, Type Ii, Susceptibility To

Diabetes Type 2

Diabetes Mellitus

Adult Onset Diabetes

Maturity Onset Diabetes

Nonketotic Diabetes

Non-Insulin Dependent Diabetes Mellitus

T2dm - [Type 2 Diabetes Mellitus]

Niddm - [Non Insulin Dependent Diabetes Mellitus]

Dm2

Dm Type Ii

Diabetic Type 2

Insulin Requiring Type 2 Diabetes

Noninsulin Dependent Diabetes

Non-Insulin-Dependent Diabetes Mellitus Without Complications

Diabetes Due To Insulin Secretory Defect

Diabetes Mellitus Due To Insulin Secretory Defect

Non-Insulin-Dependent Diabetes Of The Young

Senile Diabetes

Nonketotic Hyperglycaemia

Stable Diabetes

Marinesco-Sjogren Syndrome

Marinesco-Sjögren Syndrome

MSS

Marinesco-Garland Syndrome

Garland-Moorhouse Syndrome

Hereditary Oligophrenic Cerebello-Lental Degeneration

Oligophrenic Cerebellolenticular Degeneration

Marinesco-Sjogren Syndrome-Hypergonadotrophic Hypogonadism

Marinesco-Sjogren Syndrome-Myopathy

Marinesco-Sjogren-Garland Syndrome

Marinesco-Sjoegren Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus HSPA5 MGD MGI:95835
Canis familiaris HSPA5 VGNC VGNC:55608
Macaca mulatta HSPA5 VGNC VGNC:103272
Rattus norvegicus HSPA5 RGD RGD:2843
Bos taurus HSPA5 VGNC VGNC:59220
Felis catus HSPA5 VGNC VGNC:102938
Others HSPA5 NCBI