2. Gene
  3. FOXN2 - forkhead box N2 Gene

FOXN2 - forkhead box N2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：叉头盒 N2

种属: Homo sapiens

同用名: HTLF

基因 ID: 3344 | 基因类型: protein coding

关于 FOXN2

Cytogenetic location: 2p16.3 Genomic coordinates (GRCh38): 2:48,313,659-48,379,295 (from NCBI)

This gene has 2 transcripts (splice variants), 217 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 14.2), fat (RPKM 8.5) and 24 other tissues.

功能概要

该基因编码一个叉头结构域结合蛋白，可能在人类 T 细胞白血病病毒长末端重复序列的转录调控中发挥作用。[RefSeq 提供，2008 年 7 月]

This gene encodes a forkhead domain binding protein and may function in the transcriptional regulation of the human T-cell leukemia virus long terminal repeat. [provided by RefSeq, Jul 2008]

FOXN2 基因产物(13)

mRNA Protein Name
NM_001375442.1 NP_001362371.1 forkhead box protein N2 isoform a
NM_001375443.1 NP_001362372.1 forkhead box protein N2 isoform a
NM_001375444.1 NP_001362373.1 forkhead box protein N2 isoform a
NM_001375445.1 NP_001362374.1 forkhead box protein N2 isoform a
NM_001375446.1 NP_001362375.1 forkhead box protein N2 isoform a
NM_001375447.1 NP_001362376.1 forkhead box protein N2 isoform a
NM_001375448.1 NP_001362377.1 forkhead box protein N2 isoform a
NM_001375449.1 NP_001362378.1 forkhead box protein N2 isoform a
NM_001375450.1 NP_001362379.1 forkhead box protein N2 isoform a
NM_001375451.1 NP_001362380.1 forkhead box protein N2 isoform a
NM_001375452.1 NP_001362381.1 forkhead box protein N2 isoform a
NM_001375781.1 NP_001362710.1 forkhead box protein N2 isoform b
NM_002158.4 NP_002149.2 forkhead box protein N2 isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25609649 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FOXN2 蛋白结构

Forkhead

Forkhead: Forkhead domain (112 - 200)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 431 a.a.
蛋白主名 其他名称

forkhead box protein N2

human T-cell leukemia virus enhancer factor

FOXN2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
FOXN2 P32314 FBXW11 Homo sapiens Q9UKB1
TAP
25609649
种属内
FOXN2 P32314 FBXW11 Homo sapiens Q9UKB1
Anti Tag CoIP
33961781
种属内
FOXN2 P32314 RFX1 Homo sapiens P22670
Pull Down
25609649
种属内
FOXN2 P32314 RFX1 Homo sapiens P22670
Anti Tag CoIP
33961781
种属内
FOXN2 P32314 RFX1 Homo sapiens P22670
Anti Tag CoIP
28514442
种属内
FOXN2 P32314 RFX1 Homo sapiens P22670
TAP
25609649
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Leukemia

Leukemias

Leukaemia, Unspecified, Without Mention Of Remission

Aleukemic Leukaemia

Chronic Leukaemia

Subacute Leukaemia

Leukaemia Disorder

Leukaemia Nos
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05066 FOXN2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus FOXN2 VGNC VGNC:29096
Mus musculus FOXN2 MGD MGI:1347478
Canis familiaris FOXN2 VGNC VGNC:40961
Felis catus FOXN2 VGNC VGNC:80104
Macaca mulatta FOXN2 VGNC VGNC:72710
Rattus norvegicus FOXN2 RGD RGD:1562291
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