2. Gene
  3. Cnih2 - cornichon family AMPA receptor auxiliary protein 2 Gene

Cnih2 - cornichon family AMPA receptor auxiliary protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cnih3; CNIH-2; RGD1304930

基因 ID: 361705 | 基因类型: protein coding

关于 Cnih2

功能概要

Involved in negative regulation of anterograde synaptic vesicle transport; negative regulation of receptor localization to synapse; and regulation of neurotransmitter receptor activity. Acts upstream of or within glutamatergic synaptic transmission; localization within membrane; and regulation of membrane potential. Located in dendritic shaft and postsynaptic membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Orthologous to human CNIH2 (cornichon family AMPA Receptor auxiliary protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Cnih2 基因产物(1)

mRNA Protein Name
NM_001025132.1 NP_001020303.1 protein cornichon homolog 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20805473 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within localization within membrane IDA
IDA: 通过直接分析推断
19265014 RGD
involved in negative regulation of anterograde synaptic vesicle transport IMP
IMP: 通过突变表型推断
24094107 RGD
involved in negative regulation of receptor localization to synapse IMP
IMP: 通过突变表型推断
24094107 RGD
involved in regulation of AMPA receptor activity IDA
IDA: 通过直接分析推断
19265014 RGD
involved in regulation of AMPA receptor activity IMP
IMP: 通过突变表型推断
24094107 RGD
involved in regulation of NMDA receptor activity IMP
IMP: 通过突变表型推断
24094107 RGD
acts upstream of or within regulation of membrane potential IDA
IDA: 通过直接分析推断
19265014 RGD
acts upstream of or within synaptic transmission, glutamatergic IDA
IDA: 通过直接分析推断
19265014 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of AMPA glutamate receptor complex IDA
IDA: 通过直接分析推断
19265014 RGD
located in dendritic shaft IDA
IDA: 通过直接分析推断
19265014 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
21172611 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
24853943 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
21172611 RGD
located in postsynaptic membrane IDA
IDA: 通过直接分析推断
19265014 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein cornichon homolog 2

cornichon homolog 2

cornichon homolog 3

cornichon-like protein

Cnih2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra Cnih2 Q5BJU5 Gria1 Rattus norvegicus P19490
Anti Bait CoIP
20805473
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02885 CNIH2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cnih2 NCBI NCBI:254263
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