ME1 - malic enzyme 1 Gene

中文名称：苹果酸酶 1

种属: Homo sapiens

同用名: MES; HUMNDME

关于 ME1

功能概要

该基因编码一种细胞溶质的 NADP 依赖性酶，该酶可产生用于脂肪酸生物合成的 NADPH。这种酶的活性，即苹果酸的可逆氧化脱羧作用，将糖酵解和柠檬酸循环联系起来。该基因的表达调控是复杂的。表达增加可能是由于甲状腺激素水平升高或饮食中碳水化合物比例较高所致。[RefSeq 提供，2008 年 7 月]

This gene encodes a cytosolic, NADP-dependent Enzyme that generates NADPH for fatty acid biosynthesis. The activity of this Enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid Hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008]