ATP4B - ATPase H+/K+ transporting subunit beta Gene

中文名称：ATPase H+/K+ 转运亚基 β

种属: Homo sapiens

同用名: ATP6B

关于 ATP4B

功能概要

该基因编码的蛋白质属于 P 型阳离子转运 ATP 酶家族。胃 H+、K+-ATP 酶是一种异二聚体，由一个高分子量催化性 α 亚基和一个较小但高度糖基化的 β 亚基组成。这种酶是一种质子泵，可催化 ATP 的水解以及质膜上 H (+) 和 K (+) 离子的交换。它还负责胃酸分泌。该基因编码胃 H+、K+-ATP 酶的 β 亚基。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This Enzyme is a Proton Pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]