2. Gene
  3. ATRAID - all-trans retinoic acid induced differentiation factor Gene

ATRAID - all-trans retinoic acid induced differentiation factor Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：全反式维甲酸诱导分化因子

种属: Homo sapiens

同用名: p18; APR3; APR-3; APR--3; PRO240; C2orf28; HSPC013

基因 ID: 51374 | 基因类型: protein coding

关于 ATRAID

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,212,041-27,217,183 (from NCBI)

This gene has 6 transcripts (splice variants) and 188 orthologues. Ubiquitous expression in thyroid (RPKM 48.2), testis (RPKM 45.1) and 25 other tissues.

功能概要

该基因被认为与细胞凋亡有关，也可能与造血发育和分化有关。可变剪接位点和启动子的使用导致编码不同异构体的多个转录变体。[RefSeq 提供，2009 年 12 月]

This gene is thought to be involved in Apoptosis, and may also be involved in hematopoietic development and differentiation. The use of alternative splice sites and promotors result in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2009]

ATRAID 基因产物(2)

mRNA Protein Name
NM_001170795.4 NP_001164266.1 all-trans retinoic acid-induced differentiation factor isoform c precursor
NM_016085.5 NP_057169.2 all-trans retinoic acid-induced differentiation factor isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18388313 GOA
enables xenobiotic transmembrane transporter activity IDA
IDA: 通过直接分析推断
29745899 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of osteoblast proliferation IDA
IDA: 通过直接分析推断
21723284 GOA
involved in negative regulation of protein catabolic process IDA
IDA: 通过直接分析推断
21723284 GOA
involved in positive regulation of bone mineralization IDA
IDA: 通过直接分析推断
21723284 GOA
involved in positive regulation of osteoblast differentiation IDA
IDA: 通过直接分析推断
21723284 GOA
involved in regulation of gene expression IDA
IDA: 通过直接分析推断
21723284 GOA
involved in xenobiotic transmembrane transport IDA
IDA: 通过直接分析推断
29745899 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in lysosomal membrane IDA
IDA: 通过直接分析推断
29745899 GOA
located in nuclear envelope IDA
IDA: 通过直接分析推断
21723284 GOA
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
21723284 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

all-trans retinoic acid-induced differentiation factor

apoptosis related protein APR-3

ATRAID 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ATRAID Q6UW56 SNX9 Homo sapiens Q9Y5X1
Anti Bait CoIP
18388313
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Cloacal Exstrophy

Oeis Complex

Omphalocele-Cloacal Exstrophy-Imperforate Anus-Spinal Defect Syndrome

Omphalocele, Exstrophy Of The Cloaca, Imperforate Anus, And Spinal Defects Compl

Omphalocele, Exstrophy Of The Cloaca, Imperforate Anus, And Spinal Defects Complex

Cloacal Exstrophy Sequence

Omphalocele - Cloacal Exstrophy - Imperforate Anus - Spinal Defect

Omphalocele, Exstrophy Of The Cloaca, Imperforate Anus, And Spinal Defects

Omphalocele Exstrophy Imperforate Anus
Congenital Syphilis

Syphilis, Congenital

Congenital Syphilis, Unspecified

Mtct Of Syphilis

Mother-To-Child Transmission Of Syphilis

Syphilis Congenital

Hereditary Syphilis

Heredosyphilis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01248 ATRAID Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ATRAID VGNC VGNC:38294
Bos taurus ATRAID VGNC VGNC:54408
Felis catus ATRAID VGNC VGNC:60033
Macaca mulatta ATRAID VGNC VGNC:106132
Rattus norvegicus ATRAID RGD RGD:1311605
Mus musculus ATRAID MGD MGI:1918918
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