2. Gene
  3. KCNN2 - Kcnn2 potassium calcium-activated channel subfamily N member 2 Gene

KCNN2 - Kcnn2 potassium calcium-activated channel subfamily N member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: SK2; SKCa2; KCa2.2; SKCa 2

基因 ID: 54262 | 基因类型: protein coding

关于 KCNN2

功能概要

Enables Calmodulin binding activity and small conductance calcium-activated Potassium Channel activity. Involved in positive regulation of potassium ion transport; potassium ion transport; and regulation of neuronal synaptic plasticity. Located in dendritic spine and neuronal cell body. Is integral component of membrane. Used to study essential tremor. Orthologous to human KCNN2 (potassium calcium-activated channel subfamily N member 2). [provided by Alliance of Genome Resources, Apr 2022]

KCNN2 基因产物(2)

mRNA Protein Name
NM_001309404.1 NP_001296333.1 small conductance calcium-activated potassium channel protein 2 isoform 1
NM_019314.2 NP_062187.1 small conductance calcium-activated potassium channel protein 2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calmodulin binding IDA
IDA: 通过直接分析推断
9774106 RGD
enables calmodulin binding IMP
IMP: 通过突变表型推断
18701069 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11323678 RGD
enables small conductance calcium-activated potassium channel activity IDA
IDA: 通过直接分析推断
8781233 RGD
enables small conductance calcium-activated potassium channel activity IMP
IMP: 通过突变表型推断
14559917 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of potassium ion transport IMP
IMP: 通过突变表型推断
28917524 RGD
involved in potassium ion transport IDA
IDA: 通过直接分析推断
11323678 RGD
involved in regulation of neuronal synaptic plasticity IMP
IMP: 通过突变表型推断
21521760 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendritic spine IDA
IDA: 通过直接分析推断
21521760 RGD
located in membrane IDA
IDA: 通过直接分析推断
11323678 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
15680700 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

small conductance calcium-activated potassium channel protein 2

potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

small conductance calcium-activated potassium channel protein 2-lik

KCNN2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Kcnn2 P70604 Calm1 Rattus norvegicus P0DP29
X-Ray Diffraction
15130477
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07170 KCNN2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens KCNN2 NCBI NCBI:3781
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