2. Gene
  3. Calm2 - calmodulin 2 Gene

Calm2 - calmodulin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cam; Cam2; Camb; CaMII

基因 ID: 50663 | 基因类型: protein coding

关于 Calm2

功能概要

Enables several functions, including Enzyme binding activity; nitric-oxide synthase regulator activity; and transmembrane transporter binding activity. Involved in several processes, including activation of Adenylate Cyclase activity; regulation of calcium ion transmembrane transporter activity; and regulation of vesicle-mediated transport. Located in several cellular components, including growth cone; myelin sheath; and nucleus. Colocalizes with mitochondrial membrane and synaptic vesicle membrane. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia 4; long QT syndrome 14; and long QT syndrome 15. Orthologous to several human genes including CALM1 (Calmodulin 1). [provided by Alliance of Genome Resources, Apr 2022]

Calm2 基因产物(1)

mRNA Protein Name
NM_017326.3 NP_059022.1 calmodulin-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
15628869 RGD
enables nitric-oxide synthase binding IDA
IDA: 通过直接分析推断
20529840 RGD
enables nitric-oxide synthase regulator activity IDA
IDA: 通过直接分析推断
20529840 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11323678 RGD
enables transmembrane transporter binding IDA
IDA: 通过直接分析推断
15628869 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in establishment of protein localization to membrane IMP
IMP: 通过突变表型推断
23792689 RGD
involved in establishment of protein localization to mitochondrial membrane IMP
IMP: 通过突变表型推断
23792689 RGD
involved in positive regulation of nitric-oxide synthase activity IDA
IDA: 通过直接分析推断
20529840 RGD
involved in regulation of high voltage-gated calcium channel activity IMP
IMP: 通过突变表型推断
18322004 RGD
involved in regulation of ryanodine-sensitive calcium-release channel activity IDA
IDA: 通过直接分析推断
15628869 RGD
involved in regulation of synaptic vesicle endocytosis IMP
IMP: 通过突变表型推断
23792689 RGD
involved in regulation of synaptic vesicle exocytosis IMP
IMP: 通过突变表型推断
23792689 RGD
involved in response to amphetamine IEP
IEP: 通过表达模式推断
10854758 RGD
involved in response to corticosterone IEP
IEP: 通过表达模式推断
16503919 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
22848456 RGD
located in growth cone IDA
IDA: 通过直接分析推断
7492944 RGD
located in mitochondrial membrane IMP
IMP: 通过突变表型推断
23792689 RGD
located in myelin sheath IDA
IDA: 通过直接分析推断
19855925 RGD
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
22848456 RGD
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
22848456 RGD
located in synaptic vesicle membrane IMP
IMP: 通过突变表型推断
23792689 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calmodulin-2

calmodulin 2 (phosphorylase kinase, delta)

Calm2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra Calm1 P0DP29 Kcnn2 Rattus norvegicus P70604
ITC
22579256
Intra Calm1 P0DP29 Kcnn2 Rattus norvegicus P70604
Fluorescence Spectr
22579256
Intra Calm1 P0DP29 Kcnn2 Rattus norvegicus P70604
Solution Sedimentation
22579256
Intra Calm1 P0DP29 Kcnn2 Rattus norvegicus P70604
X-Ray Diffraction
11323678
Intra Calm1 P0DP29 Ppara Rattus norvegicus P37230
X-Ray Diffraction
18073110
Intra Calm1 P0DP29 Ppara Rattus norvegicus P37230
Fluorescence Spectr
18073110
Intra Calm1 P0DP29 Kcnn2 Rattus norvegicus H6VQ94
Solution Sedimentation
22579256
Intra Calm1 P0DP29 Kcnn2 Rattus norvegicus H6VQ94
GMS
22579256
Intra Calm1 P0DP29 Kcnn2 Rattus norvegicus H6VQ94
ITC
22579256
Intra Calm1 P0DP29 Kcnn2 Rattus norvegicus H6VQ94
Fluorescence Spectr
22579256
Intra Calm1 P0DP29 Kcnn2 Rattus norvegicus H6VQ94
X-Ray Diffraction
22579256
Cross Calm1 P0DP29 CEP290 Homo sapiens O15078
Anti Tag CoIP
23446637
Cross Calm1 P0DP29 ORAI1 Homo sapiens Q96D31
Pull Down
19706428
Cross Calm1 P0DP29 ORAI1 Homo sapiens Q96D31
Anti Tag CoIP
19706428
Cross Calm1 P0DP29 EGFR Homo sapiens P00533
Far-WB
11853560
Cross Calm1 P0DP29 EGFR Homo sapiens P00533
Crosslink
11853560
Cross Calm1 P0DP29 THOP1 Homo sapiens P52888
Pull Down
19614740
Intra Calm1 P0DP29 Thop1 Rattus norvegicus P24155
SPR
22740335
Intra Calm1 P0DP29 Cobl Rattus norvegicus D3ZUI5
Pull Down
26334624
Intra Calm1 P0DP29 Cobl Rattus norvegicus D3ZUI5
Anti Bait CoIP
26334624
Intra Calm1 P0DP29 Kcnq2 Rattus norvegicus O88943
Anti Tag CoIP
22643219
Cross Calm1 P0DP29 GRB7 Homo sapiens Q14451
Far-WB
15806159
Cross Calm1 P0DP29 SEC61A1 Canis familiaris P38377
Peptide Array
21102557
Cross Calm1 P0DP29 SEC61A1 Canis familiaris P38377
FCS
21102557
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01841 CALM2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Calm2 NCBI NCBI:805
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