2. Gene
  3. Kcnq2 - potassium voltage-gated channel subfamily Q member 2 Gene

Kcnq2 - potassium voltage-gated channel subfamily Q member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 170848 | 基因类型: protein coding

关于 Kcnq2

功能概要

Enables protein N-terminus binding activity and voltage-gated Potassium Channel activity. Involved in potassium ion transmembrane transport. Located in plasma membrane. Is integral component of plasma membrane. Part of voltage-gated Potassium Channel complex. Human ortholog(s) of this gene implicated in benign neonatal seizures and developmental and epileptic encephalopathy 7. Orthologous to human KCNQ2 (potassium voltage-gated channel subfamily Q member 2). [provided by Alliance of Genome Resources, Apr 2022]

Kcnq2 基因产物(1)

mRNA Protein Name
NM_133322.2 NP_579856.2 potassium voltage-gated channel subfamily KQT member 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12754513 RGD
enables voltage-gated potassium channel activity IDA
IDA: 通过直接分析推断
11038262 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in potassium ion transmembrane transport IDA
IDA: 通过直接分析推断
11038262 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon initial segment IDA
IDA: 通过直接分析推断
17311847 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
11038262 RGD
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
11230508 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

potassium voltage-gated channel subfamily KQT member 2

KQT-like 2

potassium channel subunit alpha KvLQT2

potassium channel, voltage-gated KQT-like subfamily Q, member 2

potassium voltage-gated channel, KQT-like subfamily, member 2

voltage-gated potassium channel subunit Kv7.2

Kcnq2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Kcnq2 O88943 Calm1 Rattus norvegicus P0DP29
Anti Tag CoIP
22643219
种属内
Kcnq2 O88943 Calm1 Rattus norvegicus P0DP29
FRET
22643219
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (18)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108577 XE991 dihydrochloride Inhibitor 99.96% 否
HY-139791 Azetukalner Activator 99.77% 否
HY-122114 ICA-27243 Activator 99.18% 否
HY-101396 ICA-069673 Activator 99.65% 否
HY-145016 HN37 Activator 99.53% 否
HY-113616A VU0364572 TFA Agonist 99.27% 否
HY-157485 Ebio1 Activator 99.99% 否
HY-18063 ML252 Inhibitor 99.9% 否
HY-108587 ICA 110381 Modulator 99.85% 否
HY-123264 RL648_81 Inhibitor 99.20% 否
HY-108577A XE991 Inhibitor / 否
HY-113616 VU0364572 Agonist / 否
HY-130070 QO-40 Activator 98.77% 否
HY-168214 Kv7.2/Kv7.3 agonist 1 Inhibitor / 否
HY-172141 Ebio2 Activator / 否
HY-RS07174 KCNQ2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-115823 ztz240 / 否
HY-18063A ML252 hydrochloride Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnq2 NCBI NCBI:3785
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