2. Gene
  3. Unc93b1 - unc-93 homolog B1, TLR signaling regulator Gene

Unc93b1 - unc-93 homolog B1, TLR signaling regulator Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Unc93b; Unc-93B1

基因 ID: 54445 | 基因类型: protein coding

关于 Unc93b1

功能概要

Enables Toll-like Receptor binding activity. Involved in intracellular protein transport and Toll-like Receptor signaling pathway. Acts upstream of or within several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; positive regulation of cytokine production; and Toll-like Receptor signaling pathway. Located in cytoplasmic vesicle; endoplasmic reticulum; and lysosome. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human UNC93B1 (unc-93 homolog B1, TLR signaling regulator). [provided by Alliance of Genome Resources, Apr 2022]

Unc93b1 基因产物(4)

mRNA Protein Name
NM_001161428.2 NP_001154900.2 protein unc-93 homolog B1 isoform b
NM_001403609.1 NP_001390538.1 protein unc-93 homolog B1 isoform c
NM_001403610.1 NP_001390539.1 protein unc-93 homolog B1 isoform d
NM_019449.3 NP_062322.3 protein unc-93 homolog B1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Toll-like receptor binding IPI
IPI: 通过物理相互作用推断
17452530 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18931679 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell antigen processing and presentation IMP
IMP: 通过突变表型推断
16415873 MGI
acts upstream of or within antigen processing and presentation IMP
IMP: 通过突变表型推断
20457904 MGI
acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II IMP
IMP: 通过突变表型推断
16415873 MGI
acts upstream of or within cell morphogenesis IMP
IMP: 通过突变表型推断
20457904 MGI
involved in intracellular protein transport IMP
IMP: 通过突变表型推断
18305481 MGI
acts upstream of or within positive regulation of interleukin-12 production IMP
IMP: 通过突变表型推断
20457904 MGI
acts upstream of or within positive regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
20457904 MGI
involved in toll-like receptor 3 signaling pathway IMP
IMP: 通过突变表型推断
16415873 MGI
involved in toll-like receptor 7 signaling pathway IMP
IMP: 通过突变表型推断
16415873 MGI
involved in toll-like receptor 9 signaling pathway IDA
IDA: 通过直接分析推断
38169466 MGI
involved in toll-like receptor 9 signaling pathway IMP
IMP: 通过突变表型推断
16415873 MGI
acts upstream of or within toll-like receptor signaling pathway IMP
IMP: 通过突变表型推断
16415873 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in early phagosome IDA
IDA: 通过直接分析推断
18305481 MGI
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
16415873 MGI
located in endosome IDA
IDA: 通过直接分析推断
18305481 MGI
located in lysosome IDA
IDA: 通过直接分析推断
18305481 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein unc-93 homolog B1

unc-93 homolog B

Unc93b1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Unc93b1 Q8VCW4 SURF4 Homo sapiens O15260
Anti Tag CoIP
21903422
种属间
Unc93b1 Q8VCW4 CLPTM1 Homo sapiens O96005
Anti Tag CoIP
21903422
种属间
Unc93b1 Q8VCW4 IRAK1 Homo sapiens P51617
Anti Tag CoIP
21903422
种属间
Unc93b1 Q8VCW4 MBOAT7 Homo sapiens Q96N66
Anti Tag CoIP
21903422
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15476 UNC93B1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Unc93b1 NCBI NCBI:81622
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