2. Gene
  3. MXRA8 - matrix remodeling associated 8 Gene

MXRA8 - matrix remodeling associated 8 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：矩阵重塑关联 8

种属: Homo sapiens

同用名: ASP3

基因 ID: 54587 | 基因类型: protein coding

关于 MXRA8

Cytogenetic location: 1p36.33 Genomic coordinates (GRCh38): 1:1,352,689-1,363,541 (from NCBI)

This gene has 10 transcripts (splice variants), 249 orthologues and 14 paralogues. Broad expression in gall bladder (RPKM 26.7), fat (RPKM 25.8) and 22 other tissues.

功能概要

预计参与胶质血脑屏障的建立。位于细胞外外泌体。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in establishment of glial blood-brain barrier. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

MXRA8 基因产物(5)

mRNA Protein Name
NM_001282582.2 NP_001269511.1 matrix remodeling-associated protein 8 isoform 2 precursor
NM_001282583.2 NP_001269512.1 matrix remodeling-associated protein 8 isoform 4
NM_001282584.2 NP_001269513.1 matrix remodeling-associated protein 8 isoform 3 precursor
NM_001282585.1 NP_001269514.1 matrix remodeling-associated protein 8 isoform 1 precursor
NM_032348.4 NP_115724.1 matrix remodeling-associated protein 8 isoform 2 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MXRA8 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (38 - 145)

V-set

V-set: Immunoglobulin V-set domain (171 - 277)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 442 a.a.
蛋白主名 其他名称

matrix remodeling-associated protein 8

limitrin

MXRA8 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MXRA8 Q9BRK3 CABP2 Homo sapiens Q9NPB3
Validated Y2H
32296183
种属内
MXRA8 Q9BRK3 ANKRD11 Homo sapiens X5D778
Validated Y2H
32296183
种属内
MXRA8 Q9BRK3 GMEB2 Homo sapiens Q9UKD1
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 MXRA8 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700876 MXRA8 Protein, Human (HEK293, His) Q9BRK3-1 (V20-Q341) ≥95%

关联疾病

疾病名称 别名
Chikungunya

Chikungunya Fever

Arbovirus A Chikungunya Type

Chik

Chikv Infection

Ck

Chikungunya Virus Infection

Chikungunya Haemorrhagic Fever

Chikungunya Viral Disease

Chikungunya Mosquito-Borne Viral Fever
Ross River Fever

Ross River Virus Disease

Ross River Virus Infection
Necatoriasis

Miner'S Anaemia

Negro Cachexia

Dochmiasis

Ground Itch Disease

Brickmaker'S Chlorosis

Coolie Itch Anaemia

Cachexia Aquosa

Dew Itch Anaemia

Brickmaker'S Anaemia

Tunnel Worker'S Anaemia

Egyptian Anaemia

Tunnel Worker'S Disease

Miner'S Cachexia

Greisinger Disease

Tropical Chlorosis

Egyptian Chlorosis

Tunnel Anaemia

Dochmiosis

Necatorosis

African Cachexia

Water Itch Anaemia

Infection Due To Necator Americanus

St Gotthard Disease

Gotthard Tunnel Disease
Esophageal Adenosquamous Carcinoma
Western Equine Encephalitis

Western Equine Encephalomyelitis

Wee

Encephalomyelitis, Western Equine

Western Equine Encephalitis Virus Infection

Wee - [Western Equine Encephalitis]

Western Equine Encephalitis Virus
Autoimmune Optic Neuritis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08867 MXRA8 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus MXRA8 VGNC VGNC:107587
Bos taurus MXRA8 VGNC VGNC:50222
Macaca mulatta MXRA8 VGNC VGNC:75088
Mus musculus MXRA8 MGD MGI:1922011
Canis familiaris MXRA8 VGNC VGNC:53426
Rattus norvegicus MXRA8 RGD RGD:1359356
Others MXRA8 NCBI
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