2. Gene
  3. Crtam - cytotoxic and regulatory T cell molecule Gene

Crtam - cytotoxic and regulatory T cell molecule Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 54698 | 基因类型: protein coding

关于 Crtam

功能概要

Enables signaling receptor binding activity. Involved in several processes, including detection of tumor cell; establishment of T cell polarity; and regulation of T cell activation. Located in immunological synapse. Orthologous to human CRTAM (cytotoxic and regulatory T cell molecule). [provided by Alliance of Genome Resources, Apr 2022]

Crtam 基因产物(2)

mRNA Protein Name
NM_001281954.2 NP_001268883.1 cytotoxic and regulatory T-cell molecule isoform 1 precursor
NM_019465.5 NP_062338.3 cytotoxic and regulatory T-cell molecule isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18329370 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
15811952 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell recognition IDA
IDA: 通过直接分析推断
15811952 MGI
involved in detection of stimulus IDA
IDA: 通过直接分析推断
15811952 MGI
involved in detection of tumor cell IDA
IDA: 通过直接分析推断
15811952 MGI
involved in establishment of T cell polarity IDA
IDA: 通过直接分析推断
18329370 MGI
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IMP
IMP: 通过突变表型推断
19752223 MGI
involved in lymphocyte migration into lymphoid organs IMP
IMP: 通过突变表型推断
24687959 MGI
involved in negative regulation of activated T cell proliferation IMP
IMP: 通过突变表型推断
18329370 MGI
involved in positive regulation of natural killer cell mediated cytotoxicity IDA
IDA: 通过直接分析推断
15811952 MGI
involved in positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target IDA
IDA: 通过直接分析推断
15811952 MGI
involved in positive regulation of type II interferon production IMP
IMP: 通过突变表型推断
18329370 MGI
involved in regulation of CD8-positive, alpha-beta T cell activation IMP
IMP: 通过突变表型推断
19752223 MGI
involved in regulation of T cell activation IMP
IMP: 通过突变表型推断
24687959 MGI
involved in regulation of T cell differentiation IMP
IMP: 通过突变表型推断
24687959 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in immunological synapse IDA
IDA: 通过直接分析推断
18329370 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15811952 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cytotoxic and regulatory T-cell molecule

class I-restricted T cell-associated molecule

class-I MHC-restricted T-cell-associated molecule

Crtam 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Crtam Q149L7 Scrib Mus musculus Q80U72
Anti Bait CoIP
18329370
种属内
Crtam Q149L7 Scrib Mus musculus Q80U72
Anti Tag CoIP
18329370
种属内
Crtam Q149L7 Scrib Mus musculus Q80U72
Confocal
18329370
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 Crtam 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77907 CRTAM/CD355 Protein, Mouse (HEK293, His) Q149L7-1 (A17-G289) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03198 CRTAM Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Crtam NCBI NCBI:56253
Canis familiaris Crtam NCBI NCBI:610296
Macaca fascicularis Crtam NCBI NCBI:102125896
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z