2. Gene
  3. Crtam - cytotoxic and regulatory T cell molecule Gene

Crtam - cytotoxic and regulatory T cell molecule Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 54698 | 基因类型: protein coding

关于 Crtam

功能概要

Enables signaling receptor binding activity. Involved in several processes, including detection of tumor cell; establishment of T cell polarity; and regulation of T cell activation. Located in immunological synapse. Orthologous to human CRTAM (cytotoxic and regulatory T cell molecule). [provided by Alliance of Genome Resources, Apr 2022]

Crtam 基因产物(2)

mRNA Protein Name
NM_001281954.2 NP_001268883.1 cytotoxic and regulatory T-cell molecule isoform 1 precursor
NM_019465.5 NP_062338.3 cytotoxic and regulatory T-cell molecule isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18329370 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
15811952 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell recognition IDA
IDA: 通过直接分析推断
15811952 MGI
involved in detection of stimulus IDA
IDA: 通过直接分析推断
15811952 MGI
involved in detection of tumor cell IDA
IDA: 通过直接分析推断
15811952 MGI
involved in establishment of T cell polarity IDA
IDA: 通过直接分析推断
18329370 MGI
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IMP
IMP: 通过突变表型推断
19752223 MGI
involved in lymphocyte migration into lymphoid organs IMP
IMP: 通过突变表型推断
24687959 MGI
involved in negative regulation of activated T cell proliferation IMP
IMP: 通过突变表型推断
18329370 MGI
involved in positive regulation of natural killer cell mediated cytotoxicity IDA
IDA: 通过直接分析推断
15811952 MGI
involved in positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target IDA
IDA: 通过直接分析推断
15811952 MGI
involved in positive regulation of type II interferon production IMP
IMP: 通过突变表型推断
18329370 MGI
involved in regulation of CD8-positive, alpha-beta T cell activation IMP
IMP: 通过突变表型推断
19752223 MGI
involved in regulation of T cell activation IMP
IMP: 通过突变表型推断
24687959 MGI
involved in regulation of T cell differentiation IMP
IMP: 通过突变表型推断
24687959 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in immunological synapse IDA
IDA: 通过直接分析推断
18329370 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15811952 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cytotoxic and regulatory T-cell molecule

class I-restricted T cell-associated molecule

class-I MHC-restricted T-cell-associated molecule

重组 Crtam 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77907 CRTAM/CD355 Protein, Mouse (HEK293, His) Q149L7-1 (A17-G289) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03198 CRTAM Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Crtam NCBI NCBI:56253
Canis familiaris Crtam NCBI NCBI:610296
Macaca fascicularis Crtam NCBI NCBI:102125896
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