2. Gene
  3. TRIM44 - tripartite motif containing 44 Gene

TRIM44 - tripartite motif containing 44 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含三方基序 44

种属: Homo sapiens

同用名: AN3; MC7; DIPB; HSA249128

基因 ID: 54765 | 基因类型: protein coding

关于 TRIM44

Cytogenetic location: 11p13 Genomic coordinates (GRCh38): 11:35,662,775-35,818,007 (from NCBI)

This gene has 2 transcripts (splice variants), 175 orthologues, 80 paralogues and is associated with 3 phenotypes. Ubiquitous expression in brain (RPKM 26.6), thyroid (RPKM 23.0) and 25 other tissues.

功能概要

该基因编码三联基序 (TRIM) 家族的成员。 TRIM 基序包括三个锌结合域，即 RING、B-box 1 型和 B-box 2 型，以及卷曲螺旋区域。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, namely a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]

TRIM44 基因产物(1)

mRNA Protein Name
NM_017583.6 NP_060053.2 tripartite motif-containing protein 44
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17577209 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of protein K48-linked ubiquitination IDA
IDA: 通过直接分析推断
23460740 GOA
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
23460740 GOA
involved in positive regulation of cytokine-mediated signaling pathway IDA
IDA: 通过直接分析推断
23460740 GOA
involved in positive regulation of defense response to virus by host IDA
IDA: 通过直接分析推断
23460740 GOA
involved in positive regulation of non-canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
23460740 GOA
involved in protein stabilization IDA
IDA: 通过直接分析推断
23460740 GOA
involved in regulation of gene expression IMP
IMP: 通过突变表型推断
26394807 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TRIM44 蛋白结构

zf-B_box

zf-B_box: B-box zinc finger (176 - 214)

  • 0
  • 100
  • 200
  • 300
  • 344 a.a.
蛋白主名 其他名称

tripartite motif-containing protein 44

关联疾病

疾病名称 别名
Aniridia 3

AN3

Aniridia, Type 3
Isolated Aniridia
Supraglottis Neoplasm

Neoplasm Of Supraglottis

Supraglottic Tumor
Gillespie Syndrome

GLSP

Aniridia, Cerebellar Ataxia And Mental Deficiency

Aniridia Cerebellar Ataxia Mental Deficiency

Aniridia, Cerebellar Ataxia, And Mental Retardation

Aniridia-Cerebellar Ataxia-Intellectual Disability Syndrome

Aniridia-Cerebellar Ataxia-Intellectual Disability

Aniridia-Cerebellar Ataxia-Mental Deficiency

Partial Aniridia-Cerebellar Ataxia-Oligophrenia

Aniridia, Cerebellar Ataxia, And Intellectual Disability
Wilms Tumor, Aniridia, Genitourinary Anomalies, And Mental Retardation Syndrome

Wagr Syndrome

11p Partial Monosomy Syndrome

Chromosome 11p13 Deletion Syndrome

Wilms Tumor, Aniridia, Genitourinary Anomalies And Mental Retardation Syndrome

11p Deletion Syndrome

Chromosome 11p Deletion Syndrome

Wagr Complex

Wilms Tumor-Aniridia-Genitourinary Anomalies-Intellectual Disability Syndrome

Deletion 11p13

WAGR

Wilms Tumor-Aniridia-Genitourinary Anomalies-Mental Retardation Syndrome

Chromosome 11p Deletion

11p Deletion

11p Monosomy

Deletion 11p

Monosomy 11p

Partial Monosomy 11p

Agr Triad

Wilms Tumor-Aniridia-Gonadoblastoma-Mental Retardation Syndrome

Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation Syndrome

Wagr Contiguous Gene Syndrome

Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

Wilms Tumor-Aniridia-Genitourinary Anomalies-Mr Syndrome

Del(11)(P13)

Monosomy 11p13

Chromosome 11, Deletion 11p
Aniridia 1

Aniridia

Congenital Aniridia

AN1

An

Cataract With Late-Onset Corneal Dystrophy

Aplasia Of Iris

Absent Iris

Irideremia

Aniridia Ii, Formerly

An2, Formerly

An2

Aniridia Type Ii

Aniridia, Type 1

An-1

Absence Of Iris

Agenesis Of Iris

Congenital Absence Of Iris

Hereditary Aniridia

Sporadic Aniridia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15048 TRIM44 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TRIM44 VGNC VGNC:36336
Canis familiaris TRIM44 VGNC VGNC:47823
Felis catus TRIM44 VGNC VGNC:66540
Rattus norvegicus TRIM44 RGD RGD:1304877
Mus musculus TRIM44 MGD MGI:1931835
Macaca mulatta TRIM44 VGNC VGNC:79168
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