ESRP1 - epithelial splicing regulatory protein 1 Gene

中文名称：上皮剪接调节蛋白 1

种属: Homo sapiens

同用名: RBM35A; RMB35A; DFNB109

基因 ID: 54845 | 基因类型: protein coding

关于 ESRP1

Cytogenetic location: 8q22.1 Genomic coordinates (GRCh38): 8:94,641,174-94,707,466 (from NCBI)

This gene has 12 transcripts (splice variants), 208 orthologues, 8 paralogues and is associated with 1 phenotype. Broad expression in esophagus (RPKM 33.0), skin (RPKM 32.6) and 15 other tissues.

功能概要

ESPR1 是一种上皮细胞类型特异性剪接调节剂 (Warzecha 等人，2009 [PubMed 19285943]) 。[OMIM 提供，2009 年 8 月]

ESPR1 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009]

ESRP1 基因产物(5)

mRNA	Protein	Name
NM_001034915.3	NP_001030087.2	epithelial splicing regulatory protein 1 isoform 2
NM_001122825.2	NP_001116297.1	epithelial splicing regulatory protein 1 isoform 4
NM_001122826.2	NP_001116298.1	epithelial splicing regulatory protein 1 isoform 3
NM_001122827.2	NP_001116299.1	epithelial splicing regulatory protein 1 isoform 5
NM_017697.4	NP_060167.2	epithelial splicing regulatory protein 1 isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables mRNA binding	IDA IDA: 通过直接分析推断	19285943	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in regulation of RNA splicing	IDA IDA: 通过直接分析推断	19285943	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in nucleus	IDA IDA: 通过直接分析推断	19285943	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ESRP1 蛋白结构

0
200
400
600
681 a.a.

蛋白主名

其他名称

epithelial splicing regulatory protein 1

RNA-binding motif protein 35A

ESRP1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	ESRP1	Q6NXG1	KRTAP19-5	Homo sapiens	Q3LI72	Y2H Array	32296183
Intra	ESRP1	Q6NXG1	KRTAP19-5	Homo sapiens	Q3LI72	Y2H Prey Pooling	32296183
Intra	ESRP1	Q6NXG1	KIF1B	Homo sapiens	O60333-2	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	KIF1B	Homo sapiens	O60333-2	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	KIF1B	Homo sapiens	O60333-2	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	ATN1	Homo sapiens	Q86V38	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	ATN1	Homo sapiens	Q86V38	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	ATN1	Homo sapiens	Q86V38	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	RBPMS2	Homo sapiens	Q6ZRY4	Anti Tag CoIP	33961781
Intra	ESRP1	Q6NXG1	RBPMS2	Homo sapiens	Q6ZRY4	Y2H Prey Pooling	32296183
Intra	ESRP1	Q6NXG1	RBPMS2	Homo sapiens	Q6ZRY4	Validated Y2H	32296183
Intra	ESRP1	Q6NXG1	RBPMS2	Homo sapiens	Q6ZRY4	Y2H Array	32296183
Intra	ESRP1	Q6NXG1	OXER1	Homo sapiens	Q8TDS5	Y2H Prey Pooling	32296183
Intra	ESRP1	Q6NXG1	OXER1	Homo sapiens	Q8TDS5	Validated Y2H	32296183
Intra	ESRP1	Q6NXG1	OXER1	Homo sapiens	Q8TDS5	Y2H Array	32296183
Intra	ESRP1	Q6NXG1	F13A1	Homo sapiens	P00488	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	F13A1	Homo sapiens	P00488	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	F13A1	Homo sapiens	P00488	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	DCTN1	Homo sapiens	Q14203-5	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	DCTN1	Homo sapiens	Q14203-5	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	DCTN1	Homo sapiens	Q14203-5	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	q9y649_human	Homo sapiens	Q9Y649	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	q9y649_human	Homo sapiens	Q9Y649	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	q9y649_human	Homo sapiens	Q9Y649	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	HSPB1	Homo sapiens	P04792	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	HSPB1	Homo sapiens	P04792	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	HSPB1	Homo sapiens	P04792	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	VIM	Homo sapiens	P08670	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	VIM	Homo sapiens	P08670	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	VIM	Homo sapiens	P08670	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	CCT5	Homo sapiens	P48643	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	CCT5	Homo sapiens	P48643	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	CCT5	Homo sapiens	P48643	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	MED25	Homo sapiens	Q71SY5	Validated Y2H	32296183
Intra	ESRP1	Q6NXG1	RNF11	Homo sapiens	Q9Y3C5	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	RNF11	Homo sapiens	Q9Y3C5	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	RNF11	Homo sapiens	Q9Y3C5	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	TTR	Homo sapiens	P02766	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	TTR	Homo sapiens	P02766	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	TTR	Homo sapiens	P02766	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	PECAM1	Homo sapiens	P16284	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	PECAM1	Homo sapiens	P16284	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	PECAM1	Homo sapiens	P16284	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
Intra	ESRP1	Q6NXG1	WFS1	Homo sapiens	O76024	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	ATXN1	Homo sapiens	P54253	Y2H Prey Pooling	25416956
Intra	ESRP1	Q6NXG1	ATXN1	Homo sapiens	P54253	Y2H Prey Pooling	32296183
Intra	ESRP1	Q6NXG1	ATXN1	Homo sapiens	P54253	Y2H Array	25416956
Intra	ESRP1	Q6NXG1	ATXN1	Homo sapiens	P54253	Y2H Array	32296183
Intra	ESRP1	Q6NXG1	KLHDC7B	Homo sapiens	Q96G42	Validated Y2H	32296183
Intra	ESRP1	Q6NXG1	KLHDC7B	Homo sapiens	Q96G42	Y2H Array	32296183
Intra	ESRP1	Q6NXG1	KLHDC7B	Homo sapiens	Q96G42	Y2H Prey Pooling	32296183
Intra	ESRP1	Q6NXG1	ATP1A3	Homo sapiens	P13637	Validated Y2H	32814053
Intra	ESRP1	Q6NXG1	ATP1A3	Homo sapiens	P13637	Y2H Array	32814053
Intra	ESRP1	Q6NXG1	ATP1A3	Homo sapiens	P13637	Y2H Pooling	32814053

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Deafness, Autosomal Recessive 109

DFNB109	Autosomal Recessive Nonsyndromic Deafness 109
Autosomal Recessive Deafness 109	Deafness, Autosomal Recessive, 109

Uterine Corpus Endometrial Carcinoma

Cleft Palate, Isolated

Cleft Palate	Isolated Cleft Palate
CPI	Cp
Palatoschisis	Cleft Palate Isolated
Uranostaphyloschisis	Congenital Fissure Of Palate
Cleft Of Secondary Palate

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS04535	ESRP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	ESRP1	VGNC	VGNC:28606
Macaca mulatta	ESRP1	VGNC	VGNC:72358
Mus musculus	ESRP1	MGD	MGI:1917326
Canis familiaris	ESRP1	VGNC	VGNC:40478
Felis catus	ESRP1	VGNC	VGNC:61965
Rattus norvegicus	ESRP1	RGD	RGD:1560481

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2024 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

ESRP1 - epithelial splicing regulatory protein 1 Gene

关于 ESRP1

功能概要

ESRP1 基因产物(5)

ESRP1 蛋白结构

ESRP1 蛋白互作信息

关联疾病

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

ESRP1 - epithelial splicing regulatory protein 1 Gene

关于 ESRP1

功能概要

ESRP1 基因产物(5)

ESRP1 蛋白结构

ESRP1 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z