1. Gene
  2. ABCF3 - ATP binding cassette subfamily F member 3 Gene

ABCF3 - ATP binding cassette subfamily F member 3 Gene

中文名称:ATP 结合盒亚家族 F 成员 3

种属: Homo sapiens

同用名: EST201864

基因 ID: 55324 | 基因类型: protein coding

关于 ABCF3

Cytogenetic location: 3q27.1 Genomic coordinates (GRCh38): 3:184,186,199-184,194,005 (from NCBI)

This gene has 18 transcripts (splice variants), 207 orthologues and 2 paralogues. Ubiquitous expression in adrenal (RPKM 33.9), testis (RPKM 16.2) and 25 other tissues.

功能概要

该基因编码 ATP 结合盒 (ABC) 转运蛋白超家族的成员。 ATP 结合盒蛋白将各种分子转运穿过细胞外膜和细胞内膜。该基因编码的蛋白质对黄病毒具有抗病毒作用。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供,2017 年 5 月]

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. The protein encoded by this gene displays Antiviral effect against flaviviruses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]

ABCF3 基因产物(4)

mRNA Protein Name
NM_001351298.2 NP_001338227.1 ATP-binding cassette sub-family F member 3 isoform 2
NM_001351299.2 NP_001338228.1 ATP-binding cassette sub-family F member 3 isoform 3
NM_001351300.2 NP_001338229.1 ATP-binding cassette sub-family F member 3 isoform 4
NM_018358.3 NP_060828.2 ATP-binding cassette sub-family F member 3 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21516116 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ABCF3 蛋白结构

ABC_tran

ABC_tran: ABC transporter (196 - 356)

ABC_tran_Xtn

ABC_tran_Xtn: ABC transporter (395 - 474)

ABC_tran

ABC_tran: ABC transporter (510 - 639)

  • 0
  • 200
  • 400
  • 600
  • 709 a.a.
蛋白主名 其他名称

ATP-binding cassette sub-family F member 3

ATP-binding cassette, sub-family F (GCN20), member 3

ABCF3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ABCF3 Q9NUQ8 FCHSD2 Homo sapiens O94868
Y2H Prey Pooling
25416956
Intra ABCF3 Q9NUQ8 FCHSD2 Homo sapiens O94868
Y2H Array
25416956
Intra ABCF3 Q9NUQ8 TRIM27 Homo sapiens P14373
Validated Y2H
26871637
Intra ABCF3 Q9NUQ8 TRIM27 Homo sapiens P14373
Y2H Array
26871637
Intra ABCF3 Q9NUQ8 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
26871637
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Felis catus ABCF3 VGNC VGNC:68301
Canis familiaris ABCF3 VGNC VGNC:37451
Mus musculus ABCF3 MGD MGI:1351656
Rattus norvegicus ABCF3 RGD RGD:1310468
Bos taurus ABCF3 VGNC VGNC:25482
Macaca mulatta ABCF3 VGNC VGNC:69583
Others ABCF3 NCBI