TMEM176A - transmembrane protein 176A Gene

中文名称：跨膜蛋白 176A

种属: Homo sapiens

同用名: GS188; MS4B1; HCA112

基因 ID: 55365 | 基因类型: protein coding

关于 TMEM176A

Cytogenetic location: 7q36.1 Genomic coordinates (GRCh38): 7:150,800,769-150,805,118 (from NCBI)

This gene has 11 transcripts (splice variants), 86 orthologues and 1 paralogue. Broad expression in liver (RPKM 172.7), kidney (RPKM 114.0) and 15 other tissues.

功能概要

预计参与树突状细胞分化的负调控。预计是膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in negative regulation of dendritic cell differentiation. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM176A 基因产物(1)

mRNA	Protein	Name
NM_018487.3	NP_060957.2	transmembrane protein 176A

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TMEM176A 蛋白结构

CD20

0
100
200
235 a.a.

蛋白主名

其他名称

transmembrane protein 176A

hepatocellular carcinoma-associated antigen 112

TMEM176A 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	TMEM176A	Q96HP8	RETREG3	Homo sapiens	Q86VR2	Y2H Array	32296183
种属内	TMEM176A	Q96HP8	RETREG3	Homo sapiens	Q86VR2	Y2H Prey Pooling	32296183
种属内	TMEM176A	Q96HP8	SGPL1	Homo sapiens	O95470	Y2H Prey Pooling	32296183
种属内	TMEM176A	Q96HP8	SGPL1	Homo sapiens	O95470	Y2H Array	32296183
种属内	TMEM176A	Q96HP8	SCD5	Homo sapiens	Q9BSN4	Y2H Prey Pooling	32296183
种属内	TMEM176A	Q96HP8	SCD5	Homo sapiens	Q9BSN4	Validated Y2H	32296183
种属内	TMEM176A	Q96HP8	SCD5	Homo sapiens	Q9BSN4	Y2H Array	32296183
种属内	TMEM176A	Q96HP8	CERS4	Homo sapiens	Q9HA82	Y2H Prey Pooling	32296183
种属内	TMEM176A	Q96HP8	CERS4	Homo sapiens	Q9HA82	Validated Y2H	32296183
种属内	TMEM176A	Q96HP8	CERS4	Homo sapiens	Q9HA82	Y2H Array	32296183
种属内	TMEM176A	Q96HP8	MFSD14B	Homo sapiens	Q5SR56	Y2H Prey Pooling	32296183
种属内	TMEM176A	Q96HP8	MFSD14B	Homo sapiens	Q5SR56	Y2H Array	32296183
种属内	TMEM176A	Q96HP8	MTIF3	Homo sapiens	Q9H2K0	Validated Y2H	32296183
种属内	TMEM176A	Q96HP8	MTIF3	Homo sapiens	Q9H2K0	Y2H Array	32296183
种属内	TMEM176A	Q96HP8	MTIF3	Homo sapiens	Q9H2K0	Y2H Prey Pooling	32296183
种属内	TMEM176A	Q96HP8	KCNK5	Homo sapiens	O95279	Y2H Prey Pooling	32296183
种属内	TMEM176A	Q96HP8	KCNK5	Homo sapiens	O95279	Y2H Array	32296183
种属内	TMEM176A	Q96HP8	TIMMDC1	Homo sapiens	Q9NPL8	Y2H Array	32296183
种属内	TMEM176A	Q96HP8	TIMMDC1	Homo sapiens	Q9NPL8	Y2H Prey Pooling	32296183
种属内	TMEM176A	Q96HP8	TIMMDC1	Homo sapiens	Q9NPL8	Validated Y2H	32296183
种属内	TMEM176A	Q96HP8	TMX2	Homo sapiens	Q9Y320	Validated Y2H	32296183
种属内	TMEM176A	Q96HP8	TMX2	Homo sapiens	Q9Y320	Y2H Prey Pooling	32296183
种属内	TMEM176A	Q96HP8	TMX2	Homo sapiens	Q9Y320	Y2H Array	32296183
种属内	TMEM176A	Q96HP8	GOLM1	Homo sapiens	Q8NBJ4	Y2H Prey Pooling	32296183
种属内	TMEM176A	Q96HP8	GOLM1	Homo sapiens	Q8NBJ4	Y2H Array	32296183
种属内	TMEM176A	Q96HP8	LITAF	Homo sapiens	Q99732	Y2H Pooling	32814053
种属内	TMEM176A	Q96HP8	LITAF	Homo sapiens	Q99732	Validated Y2H	32814053
种属内	TMEM176A	Q96HP8	LITAF	Homo sapiens	Q99732	Y2H Array	32814053
种属内	TMEM176A	Q96HP8	CD79A	Homo sapiens	P11912	Y2H Array	32296183
种属内	TMEM176A	Q96HP8	CD79A	Homo sapiens	P11912	Y2H Prey Pooling	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Hepatocellular Carcinoma

Liver Cancer	Primary Liver Cancer
HCC	Hepatoma
Malignant Neoplasm Of Liver	Liver Neoplasms
Cancer, Hepatocellular	Liver Cell Carcinoma
Lcc	Hepatoblastoma, Somatic
Hepatic Cancer	Primary Malignant Neoplasm Of Liver
Rare Tumor Of Liver And Intrahepatic Biliary Tract	Hepatocellular Carcinoma, Somatic
Hepatocellular Carcinoma, Childhood Type, Somatic	Hepatocellular Cancer, Somatic
Ca Liver - Primary	Hepatic Neoplasm
Malignant Hepato-Biliary Neoplasm	Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary
Malignant Neoplasm Of Liver, Primary	Malignant Tumor Of Liver
Neoplasm Of Liver	Non-Resectable Primary Hepatic Malignant Neoplasm
Resectable Malignant Neoplasm Of Liver	Resectable Malignant Neoplasm Of The Liver
Primary Liver Carcinoma	Primary Malignant Liver Neoplasm
Primary Cancer Of Liver	Primary Tumor Of The Liver
Rare Tumor Of Liver And Ibt	Hepatocellular Cancer
Neoplasm Of The Liver	Carcinoma, Hepatocellular
Hepatomas	Liver Neoplasm
Liver Carcinoma	Liver And Intrahepatic Biliary Tract Carcinoma
Malignant Hepatobiliary Neoplasm	Adult Primary Hepatocellular Carcinoma
Hepatoblastoma	Carcinoma Of Liver
Malignant Liver Tumour	Malignant Hepatic Tumour

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS14684	TMEM176A Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	TMEM176A	VGNC	VGNC:66292
Rattus norvegicus	TMEM176A	RGD	RGD:1310725
Mus musculus	TMEM176A	MGD	MGI:1913308
Canis familiaris	TMEM176A	VGNC	VGNC:47501
Bos taurus	TMEM176A	VGNC	VGNC:36000
Macaca mulatta	TMEM176A	VGNC	VGNC:81774

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

TMEM176A - transmembrane protein 176A Gene

关于 TMEM176A

功能概要

TMEM176A 基因产物(1)

TMEM176A 蛋白结构

TMEM176A 蛋白互作信息

关联疾病

直系同源

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TMEM176A - transmembrane protein 176A Gene

关于 TMEM176A

功能概要

TMEM176A 基因产物(1)

TMEM176A 蛋白结构

TMEM176A 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z